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HPLC测定感冒止咳颗粒剂中绿原酸和黄芩苷的含量
引用本文:王静,常新全,刘俐纯,陶春凤.HPLC测定感冒止咳颗粒剂中绿原酸和黄芩苷的含量[J].中成药,2004,26(3):206-207.
作者姓名:王静  常新全  刘俐纯  陶春凤
作者单位:1. 北京市西城区药品检验所,北京,100037
2. 华颐药业有限公司,北京,100094
3. 锦州市药品检验所,辽宁锦州,121001
摘    要:目的:建立感冒止咳颗粒剂(金银花,黄芩等)中绿原酸和黄芩苷的含量测定方法.方法:采用HPLC法测定绿原酸和黄芩苷的含量.结果:本方法线性关系良好,绿原酸的平均回收率为101.9%,RSD为1.12%;黄芩苷的平均回收率为99.2%,RSD为1.31%.结论:本方法简便、准确、重现性好,能排除其它成分的干扰,可用于该制剂的质量控制和评价.

关 键 词:HPLC法  感冒止咳颗粒  绿原酸  黄芩苷
文章编号:1001-1528(2004)03-0206-02

Determination of chlorogenic acid and baicalin in Ganmaozhike Granules by HPLC
WANG Jing ,CHANG Xin-quan ,LIU Li-chun ,TAO Chun-feng.Determination of chlorogenic acid and baicalin in Ganmaozhike Granules by HPLC[J].Chinese Traditional Patent Medicine,2004,26(3):206-207.
Authors:WANG Jing  CHANG Xin-quan  LIU Li-chun  TAO Chun-feng
Institution:WANG Jing 1,CHANG Xin-quan 2,LIU Li-chun 3,TAO Chun-feng 2
Abstract:AIM: To establish the determination method of chlorogenic acid and baicalin in Ganmaozhike Granules (Flos Lonicerae,Radix Scutellariae,etc.). METHODS : The contents of chlorogenic acid and baicalin in Ganmaozhike Granules were determined by HPLC. RESULTS : The linear velation was good. The average recovery of chlorogenic acid was 101.9%,RSD was 1.12%;The average recovery of baicalin was 99.2%,RSD was 1.31%. CONCLUSION : The method is simple,accurate and with a good reproducibility and can be used for the quality control of the granules.
Keywords:Ganmaozhike Granules  chlorogenic acid  baicalin  HPLC  
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