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戟叶酸模乙酸乙酯部位化学成分研究
引用本文:张兰胜,程永现,刘光明.戟叶酸模乙酸乙酯部位化学成分研究[J].中成药,2012,34(5):892-895.
作者姓名:张兰胜  程永现  刘光明
作者单位:1. 大理学院药学院,云南大理,671000
2. 中国科学院昆明植物研究所植物化学开放实验室,云南昆明,650204
基金项目:国家自然科学基金项目(20972165);云南省教育厅资助项目(2011C124)
摘    要:目的 研究戟叶酸模的化学成分.方法 戟叶酸模的乙醇萃取物采用硅胶柱色谱、Sephadex LH-20柱色谱等方法对化学成分进行分离及纯化,根据化合物理化性质及波谱数据鉴定其结构.结果 分离得到12个化合物,分别为大黄酚(1),大黄素(2),大黄酸(3),酸模素(4),大黄素甲醚(5),槲皮素(6),山柰酚(7),白藜芦醇(8),6-羟基芦荟大黄素(9),蒲公英甾醇乙酸酯(10),没食子酸(11),没食子酸甲酯(12).结论 化合物10和12为首次从酸模属植物中分离得到,化合物3,4,6,7,8,9,11为首次从该植物中分离得到.

关 键 词:戟叶酸模  蒽醌  化学成分

Chemical constituents of the ethyl acetate extract from Rumex hastatus D.Don
ZHANG Lan-sheng , CHENG Yong-xian , LIU Guang-ming.Chemical constituents of the ethyl acetate extract from Rumex hastatus D.Don[J].Chinese Traditional Patent Medicine,2012,34(5):892-895.
Authors:ZHANG Lan-sheng  CHENG Yong-xian  LIU Guang-ming
Institution:1(1.School of Pharmacy,Dali College,Dali 671000,China;2.Laboratory of Phytochemistry,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650204,China)
Abstract:AIM To study the chemical constituents of Rumex hastatus D.Don.METHODS Isolation and purification from ethanol extract of Rumex hastatus D.Don were carried out on the column chromatography of silica gel and Sephadex LH-20.Their structures were elucidated on basis of physicochemical properties and spectral data.RESULTS Twelve compounds were isolated and identified as chrysophanol(1),emodin(2),rhein(3),nepodin(4),physcion(5),quercetin(6),kaempferol(7),resveratrol(8),citreorosein(9),taraxasterol acetate(10),gallic acid(11),methyl gallate(12).CONCLUSION Compounds 10 and 12 were isolated from the Rumex plants for the first time.Compounds 3,4,6,7,8,9 and 11 were isolated from this plant for the first time.
Keywords:Rumex hastatus D  Don  anthraquinone  chemical constituents
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