补肾壮骨汤联合针灸及阿仑膦酸钠治疗骨质疏松症的临床效果评估

目的:探讨补肾壮骨汤联合针灸及阿仑膦酸钠治疗骨质疏松症的临床效果。方法:将2018年5月-2019年5月本院接收的骨质疏松症患者94例作为本次研究中的主要观察对象。通过电脑随机法,予以分组探讨,包括常规组(予以阿仑膦酸钠治疗)、研究组(阿仑膦酸钠,补肾壮骨汤联合针灸),各47例。结果:研究组临床疗效高于常规组(P<0.05);研究组治疗后中医证候积分、疼痛视觉模拟评分量表(Visual Analogue Scale,VAS)评分均低于常规组(P<0.05);研究组全髋以及腰椎L1-4骨密度高于常规组(P<0.05);研究组血清骨钙素(Bone Gla Protein,BGP)以及血清钙(Calcium,Ca)骨代谢指标高于常规组,碱性磷酸酶(Alkaline Phosphatase,ALP)低于常规组(P<0.05),两组血清磷(Phosphorus,P)水平无显著差异(P>0.05)。结论:应用阿仑膦酸钠治疗的同时,予以针灸联合补肾壮骨汤口服治疗,能够显著减轻患者症状,增加骨密度,优化骨代谢,效果确切,值得临床大力推荐。

Clinical effects of the Bushen Zhuanggu decoction plus acupuncture and alendronate on osteoporosis

Objective:To explore the clinical effects of the Bushen Zhuanggu decoction(补肾壮骨汤)plus acupuncture and alendronate sodium on osteoporosis.Methods:By computer random method,94 patients were divided into the routine group(treated with alendronate sodium)and study group(treated with alendronate sodium plus the Bushen Zhuanggu decoction and acupuncture),47 cases in each group.Results:The clinical efficacy in the study group was higher than the routine group(P<0.05);the scores of TCM syndromes and pain VAS in the study group were lower than the routine group(P<0.05);the bone mineral density of L1-4 in the study group was higher than the study group(P<0.05);the BGP and serum Ca in the study group were higher than the study group;and the ALP was lower than the routine group.There was no difference in serum P level between groups(P>0.05).Conclusion:The Bushen Zhuanggu decoction plus acupuncture and alendronate sodium show a definite effect,can significantly relieve symptoms,increase bone mineral density,optimize bone metabolism,and is worthy of clinical recommendation.