丹红注射液处方组分的心脑血管药理研究进展

由丹参和红花组成的中药注射剂-丹红注射液具有活血化瘀,通脉舒络的功效,可以保护血管内皮,稳定动脉粥样硬化斑块,改善微循环,能够降低冠心病患者心脏事件的发生;缩小脑心梗死范围,在缺血性心脑血管疾病方面发挥着有效的治疗作用.现代研究表明其可能机制与组分丹参和红花的成分有关,丹参和红花是临床上活血化瘀的常用药,长期的药理研究表明,其各种复杂的有效成分在治疗心脑血管疾病方面疗效显著,本文主要分析丹参和红花的有效成分在心脑血管疾病治疗方面的药理作用,进而对丹红注射液治疗心脑血管疾病的药理机制进行归纳总结.

Progress reseach of cardiovascular pharmacology inDanhong injection formulation

Traditional Chinese medicine injection, Danhong injection is composed of Radix Salvia miltiorrhiza and safflower -Danhong injection with the function of improving the blood circulation and smoothening blood flow, protecting vascular endothelial,stabilization of atherosclerotic plaques, improving microcirculation, which can reduce cardiac events in patients with coronary heart disease;narrowcerebral cardiac infarction scope and also play an effective therapeutic effect on ischemic cardiovascular and cerebrovasculardiseases. Modern research shows that the possible mechanism and components of Salvia miltiorrhiza and Safflower on components ofSalvia miltiorrhiza and safflower, promoting blood circulation and removing blood stasis is the clinical commonly used medicines,pharmacological research shows that the long-term, effective components of various complicated have obvious effect on the treatment ofcardiovascular and cerebrovascular diseases . This paper analyzes pharmacological action of Salvia miltiorrhiza and safflower in treatingcardiovascular and cerebrovascular diseases and summarizes the pharmacological mechanism and treatment of cardiovascular andcerebrovascular diseases of Danhong injection .