首页 | 本学科首页   官方微博 | 高级检索  
检索        

逍生散颗粒剂治疗干眼病的临床疗效观察
引用本文:郝晓凤,谢立科,唐由之,张志芳,肖文峥,侯乐,谢万坤,秦睿,张京,杨莉梅.逍生散颗粒剂治疗干眼病的临床疗效观察[J].环球中医药,2013,6(7):510-513.
作者姓名:郝晓凤  谢立科  唐由之  张志芳  肖文峥  侯乐  谢万坤  秦睿  张京  杨莉梅
作者单位:郝晓凤 (中国中医科学院眼科医院内障眼病二科,北京,100040); 谢立科 (中国中医科学院眼科医院内障眼病二科,北京,100040); 唐由之 (中国中医科学院眼科医院内障眼病二科,北京,100040); 张志芳 (中国中医科学院眼科医院内障眼病二科,北京,100040); 肖文峥 (中国中医科学院眼科医院内障眼病二科,北京,100040); 侯乐 (中国中医科学院眼科医院内障眼病二科,北京,100040); 谢万坤 (中国中医科学院眼科医院内障眼病二科,北京,100040); 秦睿 (中国中医科学院眼科医院内障眼病二科,北京,100040); 张京 (中国中医科学院眼科医院内障眼病二科,北京,100040); 杨莉梅 (中国中医科学院眼科医院内障眼病二科,北京,100040);
基金项目:国家自然科学基金(项目编号:81273805)
摘    要:目的研究逍生散颗粒剂治疗干眼病的临床疗效。方法将临床诊断为干眼病的80例患者,男性31例,女性49例,随机数字表法分为观察组和对照组,每组各40例。观察组给予口服逍生散颗粒剂治疗,对照组给予人工泪液玻璃酸钠滴眼液治疗,分别于治疗前、治疗后不同时间观察眼表相关指标和生活质量情况。结果观察组治疗后的临床症状积分(2.9±0.7)、干眼仪等级(2.6±0.5),均低于对照组,SchimerI评分(6.8±2.9)mm、泪膜破裂时间BUT(5.2±0.9)秒以及生活质量评分均高于对照组(P〈0.05),荧光素染色FL评分(2.1±0.8)与对照组比较,无统计学意义(P〉0.05)。结论中药逍生散颗粒剂可明显改善干眼病患者的眼表症状,大大提高其生活质量,疗效明显优于人工泪液,且稳定持久。

关 键 词:干眼病  泪膜破裂时间  逍生散颗粒剂

Clinical effect observation of Xiaosheng San Granules in treating dry eye
Institution:HAO Xiao-feng,XIE Li-ke, TANG You-zhi ,et al. Department of the second internal derangement of eye disease, Eye Hospital of China Academy of Chinese Medical Sciences, Beijing 100040, China
Abstract:Objective To study the clinical efficacy of Xiaosheng San Granules in treating dry eye. Methods 80 cases dry eye patients were randomly divided into observation group and control group, the observation group was given Xiaosheng San Granule treatment; Control group given sodium hyaluronate eye drops, before and after treatment eye surface related indexes and life quality were compared. Results Clinical symptom scores(2. 9 ±0.7) , dry eye level(2. 6 ±0. 5)of observation group were lower than those of control group ; Schimer I score (6. 8 ± 2. 9 ) mm, BUT (5.2 ± 0. 9 ) s and life quality score were higher than those of control group, FL score (2, 1 ±0. 8 ) of observation group and control group did not differ (P 〉 0. 05 ). Conclusion Xiaosheng San Granule can obviously improve the symptoms of dry eye disease of ocular surface, greatly improving the quality of life, curative effect is superior to artificial tears, stable and durable.
Keywords:Dry eye  Tear film break-up time  Xiaosheng San Granule
本文献已被 维普 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号