| 加味麻黄附子细辛汤的组方合理性与药物配比剂量研究 |
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| 引用本文： | 林瑞红,樊晖,田原,陈缤,付勇强,王珲,王英,孙科峰.加味麻黄附子细辛汤的组方合理性与药物配比剂量研究[J].中华中医药学刊,2008,26(1):123-124. |
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| 作者姓名： | 林瑞红 樊晖 田原 陈缤 付勇强 王珲 王英 孙科峰 |
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| 作者单位： | 1. 沈阳市药品快速检验所,辽宁,沈阳,110013
2. 辽宁中医药大学,辽宁,沈阳,110032 |
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| 摘 要： | 以变应性鼻炎小鼠为模型,采用均匀设计法,探讨加味麻黄附子细辛汤组方合理性及配比剂量。结果各药物在鼻敏康组方中的重要性地位依次为:附子>黄芪>防风>麻黄>细辛>白术;附子、黄芪、防风、细辛的用量与疗效呈正相关,即用量较大时疗效较好;麻黄、白术的用量与疗效呈负相关,即用量较少时疗效较好;麻黄与细辛、黄芪与附子间的交互作用呈正相关;麻黄与黄芪、黄芪与白术间的交互作用呈负相关,组方时应适当增加或减少相关药物的用量。
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| 关 键 词： | 加味麻黄附子细辛汤 变应性鼻炎 均匀设计 加味 麻黄附子细辛汤 合理性 药物配比 剂量研究 Dose Formula Decoction Aconite Herb Asarum Modified 相关药物 作用 负相关 疗效 用量 白术 防风 黄芪 |
| 文章编号： | 1673-7717(2008)01-0123-02 |
| 修稿时间： | 2007年8月17日 |
Study on Proportioning of Modified Ephedra Asarum Herb Aconite Decoction Formula and Dose |
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| LIN Rui-hong,FAN Hui,TIAN Yuan,CHEN Bin,FU Yong-qiang,WANG Hui,WANG Ying,SUN Ke-feng.Study on Proportioning of Modified Ephedra Asarum Herb Aconite Decoction Formula and Dose[J].Chinese Archives of Traditional Chinese Medicine,2008,26(1):123-124. |
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| Authors: | LIN Rui-hong FAN Hui TIAN Yuan CHEN Bin FU Yong-qiang WANG Hui WANG Ying SUN Ke-feng |
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| Abstract: | Using ethology of average incidence of allergic rhinitis mice C_57BL6 as index,uniform design is adopted to optimize formula and dose of modified ephedra asarum herb aconite decoction.the sequence of importance is:aconite>astragalus>Saposhnikovia divaricata(Turcz.) Schischk>ephedra>asarum herb>atractylodes macrocephala;aconite,astragalus,Saposhnikovia divaricata(Turcz.) Schischk,asarum herb have positive relationship with the number of grabbing nose,ephedra,atractylodes macrocephala have negetive relationship with the number of grabbing nose;the interaction of ephedra and asarum herb,astragalus and aconite are positive;ephedra and astragalus,astragalus and Saposhnikovia divaricata(Turcz.) Schischk are negative. |
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| Keywords: | modified ephedra asarum herb aconite decoction allergic rhinitis uniform design |
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