| 山核桃提取物体外抗肿瘤作用研究 |
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| 引用本文： | 胡旭姣,赵肖君,周奋,余美荣,陈银银,李瑞枝,贾永慧,丁志山.山核桃提取物体外抗肿瘤作用研究[J].中华中医药学刊,2007,25(2):369-370. |
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| 作者姓名： | 胡旭姣 赵肖君 周奋 余美荣 陈银银 李瑞枝 贾永慧 丁志山 |
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| 作者单位： | 浙江中医药大学,浙江,杭州,310053 |
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| 摘 要： | 目的：探讨山核桃的抗肿瘤作用。方法：采用极性溶剂法从山核桃叶子中分离提取出石油醚、氟仿、乙酸乙酯、正丁醇和水提取物5种提取物，采用MTT法观察其对肿瘤细胞SGC-7901增殖的抑制作用，并采用光学显微镜和电镜方法观察乙酸乙酯提取物对SGC-7901细胞凋亡的诱导作用。结果：山核桃乙酸乙酯提取物抗肿瘤作用最强，并且能够诱导肿瘤细胞凋亡。结论：山核桃叶子中有抗肿瘤物质，值得进一步深入研究。
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| 关 键 词： | 山核桃 抗肿瘤 乙酸乙酯提取物 凋亡 |
| 文章编号： | 1673-7717（2007）02-0369-02 |
| 收稿时间： | 2006-09-27 |
| 修稿时间： | 2006-09-27 |
The Anti- tumor Effects of Carya Cathayensis Sarg. Extracts in Vitro |
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| HU Xu-jiao,ZHAO Xiao-jun,ZHOU Fen,YU Mei-rong,CHEN Yin-yin,LI Rui-zhi,JIA Yong-hui,DING Zhi-shan.The Anti- tumor Effects of Carya Cathayensis Sarg. Extracts in Vitro[J].Chinese Archives of Traditional Chinese Medicine,2007,25(2):369-370. |
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| Authors: | HU Xu-jiao ZHAO Xiao-jun ZHOU Fen YU Mei-rong CHEN Yin-yin LI Rui-zhi JIA Yong-hui DING Zhi-shan |
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| Institution: | Zhejiang University of TCM, Hangzhou 310053, Zhejiang, China |
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| Abstract: | Objective: To study the anti-tumor effects of Carya Cathayensis Sarg. Methods: We extract five kinds extracts from Carya Cathayensis Sarg. leaves with light petroleum,chloroform,acetic ether,n-butanol and water. We observe the anti-tumor effects of them by MTT assay. And we also observe the induction of apoptosis of acetic ether extracts on SGC-7901. Results: The acetic ether extracts have the strongest anti-tumor effects, and it can induce SGC-7901 cell apoptosis. Conclusion: There is antitumorigenic substance in Carya Cathayensis Sarg. leaves, and it worth of study further more. |
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| Keywords: | carya cathayensis sarg anti-tumor acetic ether extracts apoptosis |
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