| 海南龙血树抗肿瘤新用途研究 |
| |
| 引用本文： | 梅文莉,戴好富,吴娇,庄令,洪葵.海南龙血树抗肿瘤新用途研究[J].中药材,2005,28(10):871-873. |
| |
| 作者姓名： | 梅文莉 戴好富 吴娇 庄令 洪葵 |
| |
| 作者单位： | 中国热带农业科学院热带生物技术研究所、热带作物生物技术国家重点实验室,海口,571101 |
| |
| 摘 要： | 目的:筛选海南龙血树的抗肿瘤活性部位.方法:分别用溶剂萃取法和大孔吸附树脂柱层析法对海南龙血树的95%乙醇提取物进行分段处理,利用MTT法测定各提取部位体外抗肿瘤活性.结果:氯仿提取物、乙酸乙酯提取物和正丁醇提取物对体外肿瘤细胞表现出较强的抑制活性,甲醇洗脱物显示了弱活性,水提取、水洗脱物和50%甲醇-水洗脱物则没有活性.在各提取物中氯仿提取物活性最强.结论:氯仿提取部位是海南龙血树主要的体外抗肿瘤活性部位.
|
| 关 键 词： | 海南龙血树 抗肿瘤活性 |
| 收稿时间： | 2005-04-11 |
| 修稿时间： | 2005-07-19 |
Study on the New Use of Antitumor of Dracaena cambodiana |
| |
| Mei Wenli,Dai Haofu,Wu Jiao,Zhuang Ling,Hong Kui.Study on the New Use of Antitumor of Dracaena cambodiana[J].Jorunal of Chinese Medicinal Materials,2005,28(10):871-873. |
| |
| Authors: | Mei Wenli Dai Haofu Wu Jiao Zhuang Ling Hong Kui |
| |
| Institution: | State Key Laboratory of Tropical Crops Biotechnology, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agriculture Sciences, Haikou 571101. |
| |
| Abstract: | Objective:To screen the antitumor extract from Dracaena cambodiana Pierre ex Gagnep.Methods:The 95% ehanol extract from Dracaena cambodiana was treated in the way of solvent partition and resin column chromatography to afford different extracts.The antitumor activities of the different extracts in vitro were determined by MTT assay.Results:The chloroform extract,ethyl acetate extract,and n-butanol extract showed strong growth inhibitory on B_(16) cells and SMMC-721 cells,and the extract of methanol elute showed weak activity,whereas the extracts of water,water elution,and 50% methanol/H_2O elution had no activity.The chloroform extract was the most active.Conclusion:The chloroform extract is the principal antitumor extract from Dracaena cambodiana. |
| |
| Keywords: | MTT |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
