| 蒺藜皂苷对乳腺癌细胞Bcap-37的体外抑制作用 |
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| 引用本文： | 孙斌,瞿伟菁,柏忠江.蒺藜皂苷对乳腺癌细胞Bcap-37的体外抑制作用[J].中药材,2003,26(2):104-106. |
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| 作者姓名： | 孙斌 瞿伟菁 柏忠江 |
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| 作者单位： | 华东师范大学生命科学学院,上海,200062 |
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| 摘 要： | 采用生长曲线法、MTT法、蛋白质含量测定以及形态学方法观察了蒺藜皂苷（STT）对于体外培养Bcap-37细胞抑制作用，结果显示：STT对于Bcap-37细胞增殖有较强的抑制作用，且呈明显的剂量与时间依赖关系，经STT作用后，细胞形态学表现为细胞变圆、皱缩，核固缩、浓聚。
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| 关 键 词： | 蒺藜皂苷 乳腺癌 Bcap－37细胞株 中药 细胞毒作用 |
| 修稿时间： | 2002年10月23 |
The Inhibitory Effect of Saponins from Tribulus terrestris on Bcap-37 Breast Cancer Cell Line in Vitro |
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| Sun Bin,Qu Weijing,Bai Zhongjiang.The Inhibitory Effect of Saponins from Tribulus terrestris on Bcap-37 Breast Cancer Cell Line in Vitro[J].Jorunal of Chinese Medicinal Materials,2003,26(2):104-106. |
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| Authors: | Sun Bin Qu Weijing Bai Zhongjiang |
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| Institution: | Life Science School of East China Normal University, Shanghai 200062. |
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| Abstract: | The inhibitory effect of saponins from Tribulus terrestris (STT) on Bcap37 breast cancer cell line were determined by cell growth curve, MTT assay, protein content assay and morphological observation.The results showed that STT had potent inhibitory effect on Bcap-37 cell line in a concentration-dependent manner. Bcap-37 cell exhibited morphological alteration, namely, cells got round and shrunk, nuclei contracted after treating with STT. |
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| Keywords: | Saponins from Tribulus terrestris(STT) Breast cancer Bcap-37 cell line |
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