| 灰毡毛忍冬花蕾水溶性化学成分研究 |
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| 作者姓名： | Chen Y Zhao YY Wu S Wang M Feng X Liang JY |
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| 作者单位： | 中国药科大学天然药物化学教研室;江苏省中国科学院植物研究所/江苏省药用植物研究开发中心 |
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| 基金项目： | “重大新药创制”科技重大专项(2009ZX09103-397) |
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| 摘 要： | 目的:研究灰毡毛忍冬花蕾的水溶性化学成分。方法:采用多种层析分离技术进行分离纯化,根据理化性质和波谱数据进行结构鉴定。结果:从灰毡毛忍冬干燥花蕾的水提物中分离得到了6个化合物,分别鉴定为:反式-芳樟醇-3,7-氧化物-6-O-β-D-葡萄糖苷(1)、secologanoside(2)、secoxyloganin(3)、绿原酸(4)、咖啡酸(5)、蔗糖(6)。结论:化合物1为首次以单体化合物形式从自然界中分离得到,化合物2、3为从该植物中首次分离得到。
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| 关 键 词： | 灰毡毛忍冬 化学成分 |
Water-soluble chemical constituents in flower buds of Lonicera macranthoides |
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| Chen Y,Zhao YY,Wu S,Wang M,Feng X,Liang JY.Water-soluble chemical constituents in flower buds of Lonicera macranthoides[J].Jorunal of Chinese Medicinal Materials,2012,35(2):231-234. |
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| Authors: | Chen Yu Zhao You-yi Wu Shuang Wang Ming Feng Xu Liang Jing-yu |
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| Institution: | Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 211198, China. chenyu@cnbg.net |
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| Abstract: | Objective:To study the water-soluble chemical constituents of the flower buds of Lonicera macranthoides.Methods:The chemical constituents were isolated and purified by means of chromatographic techniques and their structures were elucidated by spectroscopic methods.Results:Six compounds were isolated and identified as trans-linalool-3,7-oxide-6-O-β-D-glucopyranoside(1),secologanoside(2),secoxyloganin(3),chlorogenic acid(4),caffeic acid(5),sucrose(6).Conclusion:Compound 1 is isolated from nature as a single compound for the first time,compounds 2~3 are isolated from this plant for the first time. |
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| Keywords: | Lonicera macranthoides Hand -Mazz Chemical constituents |
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