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土茯苓中落新妇甙的利尿和镇痛作用
引用本文:吴丽明,张敏.土茯苓中落新妇甙的利尿和镇痛作用[J].中药材,1995,18(12):627-630.
作者姓名:吴丽明  张敏
作者单位:广东省药物研究所,广东省药物研究所 广州 510180,广州 510180
摘    要:尾静脉注射0.5 ̄2mg/kg落新妇甙能使大白鼠排尿量增加。给药后第1h尿Na^+排出增加,但对尿K^+排出没有明显改变。落新妇甙能减少化学刺激引起小鼠扭体反应次数,也能提高热板刺激反应的痛阈。

关 键 词:土茯苓  落新妇甙  中药药理学  利尿  镇痛

The Diuretic and Analgesic Action of Astilbin from Smilax glabra
Wu Liming,Zhang Min.The Diuretic and Analgesic Action of Astilbin from Smilax glabra[J].Jorunal of Chinese Medicinal Materials,1995,18(12):627-630.
Authors:Wu Liming  Zhang Min
Abstract:Astilbin was given at a dose from 0.5 to 2 mg/kg (iv), whole urine in 5 hours in rats was increased. After intravenous injection, the excretion of sodium was increased in 1h, the excretion of postassium was not significantly different compar-ed with NS group. Astilbin reduced writhing rate in mice induced by chemical stimula-tion. In hot plate test, pain threshold was raised.
Keywords:Smilax glabra  Astilbin  Diuresis  Analgesis  
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