野菊花化学成分的研究

目的：研究野菊（Chrysanthemum indicum L）的干燥头状花序中的化学成分。方法：用硅胶柱色谱法及Sephadex LH-20柱色谱法进行分离纯化,依据理化性质和光谱数据鉴定化合物结构。结果：从野菊花的80%乙醇提取物中分离得到了7个黄酮化合物,分别被鉴定为：金合欢素（acacetin、1）、金合欢素-7-O-（6″-O-乙酰基）β-D-葡萄糖苷acacetin-7-O-（6″-O-acetyl）β-D-glucopyranoside、2]、蒙花苷（linarin、3）、芹菜素-7-O-β-D-葡萄糖苷（apigenin-7-O-β-D-glucopyranoside、4）、绿原酸（chlorogenic acid、5）、香草酸（vanillic acid、6）和蔗糖（sucrose、7）。结论：化合物2、4、6和7为首次从野菊花中分离得到。

Studies on Chemical Constituents from Flowers of Chrysanthemum indicum

OBJECTIVE: To study the chemical constituents of the flowers of Chrysanthemum indicum. METHODS: Chemical constituents were isolated and purified by silica gel and Sephadex LH-20 column chromatography. The structures were identified by means of physico-chemical and spectral data. RESULTS: From the 80% ethanol extract of the material, seven compounds were isolated. Their structures were identified as acacetin(1), acacetin-7-O-(6"-O-acetyl) beta-D-glucopyranoside (2), linarin (3), apigenin-7-O-beta-D-glucopyranoside(4), chlorogenic acid (5), vanillic acid(6) and sucrose(7), respectively. CONCLUSION: Compounds 2, 4, 6 and 7 are isolated from C. indicum for the first time.