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鹿茸提取物体外抗氧化作用
引用本文:陈晓光,金淑莉,邸琳,刘新宇,宋海鹏.鹿茸提取物体外抗氧化作用[J].中药材,2003,26(10):733-734.
作者姓名:陈晓光  金淑莉  邸琳  刘新宇  宋海鹏
作者单位:1. 吉林省中医中药研究院,长春,130021
2. 长春公交医院,长春,130021
摘    要:目的:研究鹿茸提取物的体外抗氧化作用。方法:测定鹿茸提取物对NADPH-维生素c和Fe^2 -半胱氨酸系统诱发的微粒体脂质过氧化反应(MDA形成)的影响,及对黄嘌呤-黄嘌呤氧化酶系统超氧阴离子自由基(O2^-.)产生(还原型细胞色素C形成)的影响。结果:鹿茸提取物在体外能明显抑制NADPH-维生素C和Fe^2 -半胱氨酸系统诱发的大鼠脑、肝、肾微粒体脂质过氧化反应(MDA形成),及黄嘌呤黄嘌呤氧化酶系统O2^-.的产生(还原型细胞色素C形成)。结论:鹿茸提取物具有抗氧化作用。

关 键 词:鹿茸提取物  抗氧化作用  中药  脂质过氧化  丙二醛  超氧阴离子自由基  小鼠
修稿时间:2003年3月20日

Anti-lipid Peroxidaton of the Water Extract from Cornu Cervi Pantotrichum
Chen Xiaoguang ,Jin Shuli ,Di Lin ,Liu Xinyu ,Song Haipeng.Anti-lipid Peroxidaton of the Water Extract from Cornu Cervi Pantotrichum[J].Jorunal of Chinese Medicinal Materials,2003,26(10):733-734.
Authors:Chen Xiaoguang  Jin Shuli  Di Lin  Liu Xinyu  Song Haipeng
Institution:Academy of Traditional Chinese Medicine and Materia Medica of Jilin Province, Changchun 130021.
Abstract:Objective: To investigate the anti lipid peroxidation of the water extract from Cornu Cervi Pantotrichum (WECCP) in vitro Mehtods: The lipid peroxidation (malondialdehyde formation) in microsomes of rat brain, liver and kidney induced by NADPH Vit C and cyctein Fe 2+ , and the superoxide anion radical production(reduced cytochrome c formation) in xanthine xanthine oxidase system in vitro were evaluated Results: The lipid peroxidation(MDA fromation) in microsomes of rat brain, liver and kidney induced by NADPH Vit C and cyctein Fe 2+ , O 2 production(reduced cytochrome c formation) in xanthine xanthine oxidase system were significantly inhibited by WECCP Conclusion: WECCP exhibits an antioxidant activity
Keywords:Cornu Cervi Pantotrichum  Lipid peroxidation  Malondialdehyde  Superoxide anion radical  
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