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蝇蛆蛋白粉对小鼠免疫功能的影响
引用本文:覃容贵,傅平,吴建伟,国果.蝇蛆蛋白粉对小鼠免疫功能的影响[J].中药材,2007,30(6):635-637.
作者姓名:覃容贵  傅平  吴建伟  国果
作者单位:1. 贵阳医学院,药学院,贵州贵阳,550004
2. 贵阳医学院,基础医学院,贵州贵阳,550004
基金项目:贵州省技术创新项目;贵州省教育厅科研项目
摘    要:目的:探讨蝇蛆蛋白粉对正常小鼠及免疫抑制小鼠免疫功能的调节作用。方法:利用正常及环磷酰胺(Cy)所致免疫低下模型小鼠,通过血清溶血素含量检测及碳粒廓清指数测定考察蝇蛆蛋白粉对巨噬细胞巨噬功能及体液免疫功能的影响。结果:蝇蛆蛋白粉可显著提高正常小鼠半数溶血值(HC50),对吞噬指数(α)无影响;对免疫功能低下小鼠HC50无影响,但可显著提高其α值。结论:蝇蛆蛋白粉可有效地增强正常小鼠体液免疫功能;对Cy造成的免疫功能低下有一定的预防和治疗作用。

关 键 词:蝇蛆蛋白粉  免疫活性  小鼠
文章编号:1001-4454(2007)06-0635-03
修稿时间:2006-11-20

Study on Immunological Effect of Housefly Protein in Mice
QIN Rong-gui,FU Ping,WU Jian-wei,GUO Guo.Study on Immunological Effect of Housefly Protein in Mice[J].Jorunal of Chinese Medicinal Materials,2007,30(6):635-637.
Authors:QIN Rong-gui  FU Ping  WU Jian-wei  GUO Guo
Institution:1. Pharmaceutical College; 2. Basic Medical College, Guiyang Medical Institute, Guiyang 550004, China
Abstract:Objective: To study the immunological effect of the housefly protein in mice.Methods: The housefly protein was given orally in normal and Cyclophosphamide(CY) immunosuppressive mice,and then the indexes of the clearance rate of carbon particles and the serum hemolysin against SRBC were detected.Results: The housefly protein could increase HC50 significantly in the normal mice,but could not in the CY immunosppressive mice.It could increase phagocytic index significantly in the normal mice,but could not in the CY immunosuppressive mice.Conclusion: The results suggest that the housefly protein can promote humoral immunity functions of normal mice.It has distinct preventive and cure effect on the CY immunosuppressive.
Keywords:Housefly protein  Immuncompetence  Mouse
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