2型糖尿病中医证型的筛选研究

目的：确定2型糖尿病的规范化证型，并展开对中医证候分型与胰岛素抵抗、胰岛功能相关性的探讨，为2型糖尿病的临床辨证提供客观诊断依据。方法：采用流行病学研究方法，选取符合标准的327例患者，收集其四诊信息，填写CRF表，最后将所有资料录入数据库。通过统计软件SPSS13．0系统聚类处理，结合专家组评定意见，筛选出2型糖尿病的中医证候群。结果：2型糖尿病可分为湿热内蕴、气阴两虚、肾阳不足及瘀血阻络4个证型，气阴两虚证所占比例最多，瘀血贯穿糖尿病的发病全过程。结论：本研究按照严格的标准收集四诊资料，采用统计学分析处理，筛选了2型糖尿病的4个规范化中医证型，具有较高可信度，可供临床和研究参考。

Research of Chinese Medical Patterns for Type Ⅱ Diabetes

Objective：To determine standardized patterns for Type Ⅱ Diabetes and explore their correlation with insulin resistance and insulin functions so as to provide objective diagnostic proofs for clinic pattern differentiation. Methods ： We selected 327 subjects according to epidemiologic study methods, collected outcomes of four examinations, filled in CRFs, and filed data into the databank. The Chinese medical patterns for Type Ⅱ Diabetes were determined by statistic analysis with Software SPSS13.0 plus advices from experts. Results：Type Ⅱ Diabetes can be categorized to four patterns, i.e. internal retention of damp-heat, deficiency of both qi and yin, inadequate Kidney yang and obstruction of collaterals by blood stasis. Deficiency of qi and yin was dominant, and blood stagnation accompanied the whole progress of Type 11 Diabetes. Conclusion：Four standardized Chinese medical patterns for Type Ⅱ Diabetes were determined on strictly collected 4 examinations information by statistic analysis. The outcome was relatively highly reliable for clinical and research reference.