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竹节参皂苷类化学成分的研究
引用本文:邹海艳,赵,晖,邱,葵,崔小桂,于,萍.竹节参皂苷类化学成分的研究[J].世界中医药,2012,7(6):565-566.
作者姓名:邹海艳          崔小桂    
作者单位:1. 首都医科大学中医药学院,北京,100069
2. 首都医科大学附属北京朝阳医院药事部
基金项目:首都中医药与护理学研究专项基金(11ZYH07),北京市属高等学校人才强教深化计划"中青年骨干人材培养计划"项目,北京市优秀人材资助项目
摘    要:目的:对竹节参中的皂苷类化学成分进行研究。方法:采用正丁醇萃取,制备高效液相色谱等方法分离制备竹节参中的皂苷类成分,应用波谱等方法鉴定化合物的结构。结果:从竹节参中分离得到了5个皂苷类化合物,分别鉴定为巨花雪胆皂苷B(1),竹节参皂苷Ⅴ(2)、IV(3)、IVa(4)和Cynarasaponin C(5)。结论:化合物1和化合物5为首次从人参属植物中分离得到。

关 键 词:竹节参  化学成分  三萜皂苷  结构鉴定
收稿时间:2012/7/18 0:00:00

Study on Saponins of Panax Japonicus Rhizome
Zou Haiyan,Zhao Hui,Qiu Kui,Cui Xiaogui,Yu Ping.Study on Saponins of Panax Japonicus Rhizome[J].World Chinese Medicine,2012,7(6):565-566.
Authors:Zou Haiyan  Zhao Hui  Qiu Kui  Cui Xiaogui  Yu Ping
Institution:1 School of Traditional Chinese Medicine, Capital Medical University, Beifing, China, Post code: 100069 ;2 Department of Pharmacology, Beijing Chaoyang Hospital Affiliated to Capital University of Medical Sciences)
Abstract:Objective:To study the the saponins of Panax japonicus. Methods:Solvent extraction and preparative HPLC were used for separation, and their structures were identified by spectral analysis. Results:Five saponins were obtained and identified as Hemsgiganosides B (1), Chikusetsusaponin V (2), IV (3), IVa (4) and Cynarasaponin C (5). Conclusion:Hemsgiganosides B (1) and Cynarasaponin C (5) were isolated from the plants of genus Panax for the first time.
Keywords:Panax japonicus  Chemical constituents  Triterpenoid saponins  Structure identification
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