醒脑开窍针刺法治疗血管性痴呆患者的疗效

目的:探究醒脑开窍针刺法对血管性痴呆(VD)患者的简易智能状态量表(MMSE)评分、Barthel指数及基质金属蛋白酶(MMP)的影响。方法:选取2017年1月至2018年1月湖南省脑科医院收治的血管性痴呆患者共110例作为研究对象,随机分为观察组和对照组,每组55例。对照组采用常规针刺疗法;观察组采用醒脑开窍针刺疗法,2组疗程均为4周。比较2组患者治疗后治疗有效率及治疗前后MMSE、Barthel指数及MMP水平。结果:观察组、对照组的治疗有效率分别为92.72%和78.18%,差异有统计学意义(P<0.05);治疗后2组患者MMSE和Barthel指数均显著升高,差异有统计学意义(P<0.05),且观察组高于对照组,差异有统计学意义(P<0.05);治疗后2组患者的MMP-2和MMP-9值均下降,差异有统计学意义(P<0.05),且观察者组患者的MMP-2和MMP-9低于对照组,差异有统计学意义(P<0.05)。结论:醒脑开窍针刺法对VD患者疗效显著,能够有效缓解痴呆症状。

Effects in Patients with Vascular Dementia Using Acupuncture Method of Inducing Resuscitation

To explore the effects on MMSE scores, Barthel indexes and matrix metalloproteinase (MMP) in patients with vascular dementia (VD) by using acupuncture method of inducing resuscitation.Methods:A total of 110 patients with VD in Hunan Brain Hospital were randomly divided into an observation group (55 cases) and a control group (55 cases).The control group was treated with routine acupuncture method while the observation group was treated with acupuncture method of inducing resuscitation.There were 2 weeks of treatment for the 2 groups.The total effective rates, MMSE scores, Barthel indexes and levels of MMP were compared between the 2 groups.Results:The total effective rates in the observation group and the control group were 92.72 % and 78.18 %, respectively, with significant difference (P<0.05).After treatment, the MMSE scores and Barthel indexes in the 2 groups increased significantly (P<0.05), and those in the observation group were higher than those in the control group, with significant difference (P<0.05).After treatment, the levels of MMP-2 and MMP-9 in the 2 groups decreased significantly (P<0.05); Moreover, those in the observation group were lower than those in the control group, with significant difference (P<0.05).Conclusion:Acupuncture method of inducing resuscitation is an effective therapy in treating VD patients and can effectively relieve the symptoms of dementia, which is worthy for further promotion and application.