明目复元汤联合中药穴位贴敷治疗视神经萎缩的疗效观察

目的：观察明目复元汤联合中药穴位贴敷治疗视神经萎缩患者的临床疗效。方法：按随机数字表法将符合标准的74例患者（108眼）分为治疗组和对照组，其中治疗组38例（52眼），对照组36例（56眼），治疗组予以口服明目复元汤及患侧太阳穴贴敷中药药膏治疗，对照组采用曲克芦丁、肌苷、腺苷钴胺、胞磷胆碱和维生素B1治疗。结果：治疗组视力显效9眼，显效率17.31％，总有效率75.00％。对照组显效3眼，显效率5.36％，总有效率60.71％。治疗组视野平均缺损显效8眼，显效率15.38％，总有效率78.85％。对照组显效2眼，显效率3.58％，总有效率58.93％。治疗组视觉诱发电位（ Visual Evoked Poten-tial，F-VEP） P100波潜伏期显效8眼，显效率15.38％，总有效率76.92％。对照组显效3眼，显效率5.36％，总有效率58.93％。2组比较，视力、视野平均缺损和F-VEP P100波潜伏期的总有效率差异均无统计学意义（P＞0.05），显效率差异均有统计学意义（ P＜0.05）。结论：明目复元汤联合中药穴位贴敷对于提高视神经萎缩患者视力、减小视野平均缺损、缩短F-VEP P100波潜伏期均有一定疗效。

Study on the Therapeutic Effects of Eyesight Recovery Decoction Combined with TCM Acupoint Application in the Treatment of Optic Atrophy

Objective：To observe the clinical curative effect of eyesight rehabilitation decoction combined with traditional Chinese medi -cine acupoint application in treatment of patients with optic atrophy .Methods：A total of 74 cases patients （108 eye） were divided into observation group and against group according to random digital table ：observation group 38 cases （52 eye）, control group 36 cases （56 eye）.Observation group received oral eyesight recovery decoction and Chinese medicine ointment treatment on the temple that is on the same side with the diseased eye .Control group used troxerutin , muscle glycoside, cobamamide, citicoline, and vitamin B1 treatment. Results：A total of 9 patients in the observation group showed significant improvements , demonstrating 17.31% efficiency, total effec-tive rate being 75.00 %.Control group had effects on 3 eyes, demonstrating 5.36 %efficiency, total effective rate being 60.71%.In the observation group, 8 cases showed improvements on vision defects , demonstrating 15.38%efficiency, with total effective rate being 78.85 %.Control group had improvements on 2 eyes, showing 3.58%efficiency, with total effective rate being 58.93%.In the ob-servation group, F-VEP P100 wave incubation period was effective on 8 eyes, 15.38%efficiency, with total effective rate being 76.92%.Control group had an effect on 3 eyes, 5.36 %efficiency, with total effective rate being 58.93%.The two groups showed no sig-nificant difference in terms of eyesight , vision defect and F-VEP P100 wave incubation period （P〉0.05）, while differences of efficacy was significant （P〈0.05）.Conclusion：Eyesight recovery decoction combined with TCM acupoint application is effective in improving vision in patients with optic nerve atrophy .It generally reduces field of vision defects , and shorten F-VEP P100 wave incubation period .