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| 胃灵颗粒治疗消化性溃疡的临床与实验研究 | |
| 引用本文： | 林禾禧,王奕珊,朱国曙,张闽光,林振川,陈奕昭,何成龙,吕方,杨春波,谢振家.胃灵颗粒治疗消化性溃疡的临床与实验研究[J].中医杂志,2005,46(8):590-592. |
| 作者姓名： | 林禾禧 王奕珊 朱国曙 张闽光 林振川 陈奕昭 何成龙 吕方 杨春波 谢振家 |
| 作者单位： | 1. 福建省泉州市中医院,泉州市温陵南路215号,362000 2. 福建中医学院附属第二医院 3. 福建省新药药理研究基地 |
| 摘 要： | 目的:研究胃灵颗粒对消化性溃疡愈合质量(QOUH)和大鼠乙酸慢性胃溃疡愈合质量的影响.方法:用随机分组的方法,观察临床消化性溃疡的复发率并用苏木精-伊红染色对大鼠愈合性胃溃疡再生黏膜进行定量观察,测定胃壁结合黏液量、胃酸、胃蛋白酶活性.结果:胃灵颗粒组能降低消化性溃疡的复发率,改善胃溃疡大鼠胃黏膜的组织损伤并提高胃壁结合黏液量,减少胃酸的排出.结论:胃灵颗粒能提高QOUH,是临床抗消化性溃疡复发的可能机制之一. |
| 关 键 词： | 消化性溃疡/中医药疗法 @胃灵颗粒剂 |
| 收稿时间： | 07 16 2004 12:00AM |
| 修稿时间： | 2004-07-162005-01-10 |
Clinical and Experimental Study on Weiling Granule for Treatment of Peptic Ulcer |
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| Lin HeXi;Wang YiShan;Zhu GuoShu;Zhang MinGuang;Lin ZheChuan;Chen YiZhao;He ChengLong;Lv Fang;Yang ChunBo;Xie ZheGu.Clinical and Experimental Study on Weiling Granule for Treatment of Peptic Ulcer[J].Journal of Traditional Chinese Medicine,2005,46(8):590-592. | |
| Authors: | Lin HeXi;Wang YiShan;Zhu GuoShu;Zhang MinGuang;Lin ZheChuan;Chen YiZhao;He ChengLong;Lv Fang;Yang ChunBo;Xie ZheGu |
| Institution: | ZhiDao;ZhiDao |
| Abstract: | Objective:To study on effects of Welling Granule on union of peptic ulcer and the gastrical ulcer induced by acetic acid in the rat. Methods:With random grouping method,the clinical recurrence rate of peptic ulcer,and regenerated macosa of healing gastric ulcer in the rat was investigated quantitatively with hematoxylin-eosin staining,and gastric wall combining macus amount,gastric acid and pepsin activity were determined.Results:Weiling Granule could decrease the recurrence rate of peptic ulcer,improve injury of the tissue of gastric macosa in the rat,increase gastric wall combining mucus amount,and decrease secretion of gastric acid.Conclusion:Weiling Granule can increase quality of ulcerative healing,which is possibly one of the mechanisms of anti- recurrence of peptic ulcer clinically. |
| Keywords: | Peptic ulcer/TCM therapy @ Weiling Granule |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |