慢性乙型肝炎中医证型分布规律研究

目的研究慢性乙型肝炎的中医证型分布情况,揭示其证候分布规律。方法通过计算机检索和手工检索国内外有关中医药治疗慢性乙型肝炎的文献,将符合纳入标准的的522篇文献进行证型分布情况统计和评价。结果出现频次前8位的证型分别为肝郁脾虚、肝肾阴虚、脾肾阳虚、瘀血阻络、湿热中阻、肝胆湿热、气滞血瘀、肝郁气滞。其中,湿热中阻、肝胆湿热、湿热蕴结、湿热内蕴、湿热蕴脾可以用“湿热内阻”统括。结论肝郁脾虚和湿热内阻是慢性乙型肝炎最主要的证型。

Chinese Medical Pattern Distribution of Chronic Type Hepatitis B

Objective To study Chinese medical pattern distribution of chronic hepatitis B(HB).Methods Totally 522 articles on Chinese medicine for chronic HB were retrieved and estimated,aiming at pattern distribution evaluation.Results The top eight patterns according to frequency were:liver depression and spleen defficiency,liver-kidney yin deficiency,spleen-kidney yang deficiency,static blood obstructing the network vessels,damp-heat obstructing the center,liver-gallbladder damp-heat,qi stagnation and blood stasis,and liver depression and qi stagnation.Damp-heat causing internal obstruction consisted of damp-heat obstructing the center,liver-gallbladder damp-heat,damp-heat brewing and binding,damp-heat brewing internally and damp-heat brewing in the spleen.Conclusion Primary patterns of chronic HB are liver depression and spleen defficiency and damp-heat causing internal obstruction.