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解毒活血中药对急性冠状动脉综合征患者冠状动脉介入术后炎症因子的影响
引用本文:赵静,宫丽鸿,高峰,郭秋影,黄欢,汪雨静.解毒活血中药对急性冠状动脉综合征患者冠状动脉介入术后炎症因子的影响[J].中医杂志,2011(18):1554-1557.
作者姓名:赵静  宫丽鸿  高峰  郭秋影  黄欢  汪雨静
作者单位:1. 辽宁中医药大学2009级硕上研究生,辽宁省沈阳市崇山东路79号,110032
2. 辽宁中医药大学附属医院心内二科
基金项目:辽宁省科学技术计划重大、重点项目资助,沈阳科学技术计划资助项目
摘    要:目的观察解毒活血中药对急性冠状动脉综合征患者(ACS)经皮冠状动脉介入治疗(PCI)术后炎症反应的作用。方法将50例ACS患者PCI术后随机分为治疗组和对照组各25例,对照组予常规西药,治疗组在对照组基础上加用活血解毒中药,疗程均为30天,检测治疗前后血清细胞间黏附分子-1(ICAM-1)和P-选择素水平,并进行中医证候评分并观察中医证候疗效。结果治疗后两组患者血清ICAM-1及P-选择素与治疗前比较均有明显下降(P<0.05),治疗后两组间比较差异亦有统计学意义(P<0.05)。两组患者治疗前后中医证候积分差异均有统计学意义(P<0.05),治疗后两组间比较差异亦有统计学意义(P<0.05)。治疗组总有效率92%,对照组总有效率72%,两组总有效率比较差异有统计学意义(P<0.05)。结论解毒活血中药能明显降低ACS患者PCI术后血清ICAM-1和P-选择素表达水平,表明解毒活血中药能抑制PCI术后炎性反应。

关 键 词:急性冠脉综合征  解毒活血  细胞黏附分子-1  P-选择素  经皮冠状动脉介入术

Influence of Detoxificating and Activating Blood Herbal Medicine on Inflammatory Factors of the Patients with Acute Coronary Syndrome after Percutaneous Coronary Intervention
ZHAO Jing,GONG Lihong,GAO Feng,GUO Qiuying,HUANG Huan,WANG Yujing.Influence of Detoxificating and Activating Blood Herbal Medicine on Inflammatory Factors of the Patients with Acute Coronary Syndrome after Percutaneous Coronary Intervention[J].Journal of Traditional Chinese Medicine,2011(18):1554-1557.
Authors:ZHAO Jing  GONG Lihong  GAO Feng  GUO Qiuying  HUANG Huan  WANG Yujing
Institution:ZHAO Jing1,GONG Lihong2,GAO Feng1,GUO Qiuying1,HUANG Huan1,WANG Y ujing1 (1.Liaoning University of Chinese Medicine,Shenyang 110032,2.The Affiliated Hospital of Liaoning University of Chinese Medicine)
Abstract:Objective To observe the influence of detoxificating and activating b lood herbal medicine on inflammation reaction of the patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI) .Methods Fifty ACS pati ents after PCI were randomized into treatment group and control group with 25 in each.The control grou p was given the routine western medicine treatment,the treatment group was administered detoxificating and activating blood herbal medicine additionally.The levels of seru...
Keywords:acute coronary syndrome (ACS)  detoxificating and activating blood  intercellular adhesive molecule-1 (ICAM-1)  P-selection  percutaneous coronary intervention (PCI)  
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