| 补肺通络丸联合甲氨蝶呤治疗类风湿关节炎早期肺间质病变32例临床观察 |
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| 引用本文： | 谢宇杰.补肺通络丸联合甲氨蝶呤治疗类风湿关节炎早期肺间质病变32例临床观察[J].中医杂志,2011,52(14):1213-1216. |
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| 作者姓名： | 谢宇杰 |
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| 作者单位： | 重庆医科大学附属第一医院中西医结合科,重庆市渝中区袁家岗友谊路1号,400016 |
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| 摘 要： | 目的观察补肺通络丸联合甲氨蝶呤治疗早期类风湿关节炎肺间质病变(RA-ILD)的临床疗效及安全性。方法选择符合纳入标准的患者64例,随机分为治疗组和对照组各32例,治疗组在甲氨蝶呤基础上口服补肺通络丸,对照组继续单用甲氨蝶呤,治疗6个月后比较两组患者肺功能指标及高分辨率CT(HRCT)治疗前后的变化。结果治疗后治疗组的肺总量(TLC)、一氧化碳弥散量(DLCO)较治疗前明显改善(P<0.01),其HRCT评分较治疗前减小(P<0.05),两组治疗后的TLC、DLCO、HRCT结果比较差异有统计学意义(P<0.01或P<0.05)。结论补肺通络丸联合甲氨蝶呤治疗早期RA-ILD能明显改善肺功能,缩小肺间质病变面积,疗效确切,安全性好。
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| 关 键 词： | 类风湿关节炎 肺间质病变 补肺通络丸 甲氨蝶呤 肺功能 高分辨率CT |
Clinical Observation on Bufei Tongluo Wan Combined with Methotrexate for Rheumatoid Arthritis Associated Early Interstitial Lung Disease: A 32 Cases Report |
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| XIE Yujie.Clinical Observation on Bufei Tongluo Wan Combined with Methotrexate for Rheumatoid Arthritis Associated Early Interstitial Lung Disease: A 32 Cases Report[J].Journal of Traditional Chinese Medicine,2011,52(14):1213-1216. |
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| Authors: | XIE Yujie |
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| Institution: | XIE Yujie(The First Affiliated Hospital,Chongqing University of Medical Sciences,Chongqing 400016) |
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| Abstract: | Objective To observe the effect and safety of Bufei Tongluo Wan (Bolus for tonifying the lung and removing obstruction of meridians) combined with methotrexate on rheumatoid arthritis associated interstitial lung disease (RA-ILD) in an early stage.Methods Sixty-four patients were randomized into two groups with 32 in each.The observation group was treated with Bufei Tongluo Wan and methotrexate for oral taking,while the control group treated with methotrexate only in continuation.After treatment for six mon... |
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| Keywords: | rheumatoid arthritis associated interstitial lung disease (RA-ILD) Bufei Tongluo Wan (Bolus for tonifying the lung and removing obstruction of meridians) methotrexate lung function high-resolution CT |
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