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中药配合氦氖激光对黄褐斑患者脂质过氧化物、超氧化物歧化酶的影响
引用本文:吴艳华,李其林,杨秀文.中药配合氦氖激光对黄褐斑患者脂质过氧化物、超氧化物歧化酶的影响[J].中医杂志,2007,48(1):29-31.
作者姓名:吴艳华  李其林  杨秀文
作者单位:广州市红十字会医院中医科、皮肤科,广东省广州市同福中路396号,510220
基金项目:广东省广州市科技局科技攻关项目
摘    要:目的观察中药汤剂、川芎嗪配合氦氖激光对黄褐斑患者脂质过氧化物(LPO)和超氧化物歧化酶(SOD)的影响。方法90例黄褐斑患者随机分为两组,治疗组54例,采用自拟补肾疏肝化瘀方、川芎嗪配合氦氖激光治疗。对照组36例,采用口服维生素E、维生素C,20%壬二酸霜外涂治疗。结果治疗组总有效率79.6%,明显优于对照组(P<0.05)。治疗组治疗后LPO明显降低(P<0.01),SOD明显升高(P<0.05)。结论自拟补肾疏肝化瘀方、川芎嗪配合氦氖激光治疗黄褐斑,具有抗氧化作用,临床可获得较好疗效。

关 键 词:黄褐斑  中医药疗法  脂质过氧化物  氦氖激光  川芎嗪
修稿时间:2006-03-162006-08-08

Effect of Chinese Medicinals Combined with He-Ne Laser on Lipoperoxide and Superoxide Dismutase in Chloasma Patients
WU Yan-hua,LI Qi-lin,YANG Xiu-wen.Effect of Chinese Medicinals Combined with He-Ne Laser on Lipoperoxide and Superoxide Dismutase in Chloasma Patients[J].Journal of Traditional Chinese Medicine,2007,48(1):29-31.
Authors:WU Yan-hua  LI Qi-lin  YANG Xiu-wen
Abstract:Objective To observe the effect of Chinese decoction and ligustrazin Hydrochloride Injection combined with He-Ne laser on lipoperoxide (LPO) and Superoxide dismutase (SOD) in chloasma patients.Methods Ninety cases of chloasma were randomly divided into two groups.The treatment group (n=54) was treated by self-prepared Kidney-Supplementing Liver-Coursing Stasis-Transforming Formula,Ligustrazin Hydrochloride Injection and He-Ne laser therapy.Vit E and Vit C were orally taken and 20% Azelaic Acid cream was given for external use to 36 patients in control group.Results The total efficacy of treatment group (79.6%) was superior to that of control group (P<0.05).After treatment LPO decreased while SOD increased remarkedly in treatment group (P<0.05 or P<0.01).Conclusion Kidney-Supplementing Liver-Coursing Stasis-Transforming Formula,Ligustrazin Hydrochloride Injection and He-Ne laser therapy has anti-oxidation capacity and better efficacy for chloasma.
Keywords:Chloasma  TCM therapy  Lipoperoxide  He-Ne laser  Ligustrazin
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