| 血府逐瘀浓缩丸防治家兔经皮血管腔内成形术后再狭窄的研究 |
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| 引用本文： | 史大卓,李平.血府逐瘀浓缩丸防治家兔经皮血管腔内成形术后再狭窄的研究[J].中医杂志,1997,38(11):685-687. |
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| 作者姓名： | 史大卓 李平 |
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| 作者单位： | 中国中医研究院西苑医院心血管病研究室，中国中医研究院西苑医院心血管病研究室，中国中医研究院西苑医院心血管病研究室，中国中医研究院西苑医院心血管病研究室，中国中医研究院西苑医院心血管病研究室，中国中医研究院西苑医院心血管病研究室，北京医科大学第三临床医学院心血管内科，北京医科大学第三临床医学院心血管内科，北京医科大学第三临床医学院心血管内科，北京医科大学第三临床医学院心血管内科 北京海淀区西苑 100091，北京海淀区西苑 100091，北京海淀区西苑 100091，北京海淀区西苑 100091，北京海淀区西苑 100091，北京海淀区西苑 100091 |
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| 基金项目： | “八五”国家科技攻关课题 |
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| 摘 要： | 本实验采用家兔髂动脉粥样硬化模型,研究血府逐瘀浓缩丸(简称浓缩丸)对经皮血管腔内成形术(PTA)后再狭窄的影响,结果显示:PTA后4周家兔髂动脉管腔直径,浓缩丸大剂量组明显大于空白对照组和美降脂组(P
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| 关 键 词： | 血府逐瘀汤/治疗应用 血管成形术/副作用 缩窄 病理性/中医药疗法 |
Prevention and Treatment of Re -stenosis after PTA in Rabbit with Xuefu Zhuyu Concentrated Pills |
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| Shi Dazhuo,Xu Fengqin,Ma Xiaochang,et al..Prevention and Treatment of Re -stenosis after PTA in Rabbit with Xuefu Zhuyu Concentrated Pills[J].Journal of Traditional Chinese Medicine,1997,38(11):685-687. |
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| Authors: | Shi Dazhuo Xu Fengqin Ma Xiaochang |
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| Institution: | Shi Dazhuo,Xu Fengqin,Ma Xiaochang,et al. Xiyuan Hospital,Xiyuan,Beijing
100091 |
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| Abstract: | Rabbit model of arteriosckrosis of iliac artery was used in this experiment. Results showed: after 4 weeks of PTA operation, the calibre of the artery in large dose concentrated pill (LCP) group was obviously larger than that of the western drug group and Lovastatin group (P<0. 01 andP<0. 001). For the rate of restenosis at the site of vessel lesion, the LCP group was obviously lower than that of the blank control group (P<0. 005). For the thickness of iliac arterial intima, the LCP group was markedly smaller that of the Lovastatin and blank control groups (P<0. 01-P < 0. 001). By transmission electro - microscopic observation, the organelle in the vascular smooth muscle cells in LCP and small - duo group contained myofilaments well differentiated, while those in the Lovastatin and blank control groups were much more and in proliferated condition. The level of blood lipids in all 4 groups A weeks after PTA operation showed no significant difference. |
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| Keywords: | Xuefu Zhuyu Decoction/therapeutic application/side -effectstenosis |
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