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脑心通胶囊对代谢综合征患者左心室肥厚的影响
引用本文:刘运芳,赵玉霞,于会明,钟丽红,张运.脑心通胶囊对代谢综合征患者左心室肥厚的影响[J].中医杂志,2006,47(8):594-595.
作者姓名:刘运芳  赵玉霞  于会明  钟丽红  张运
作者单位:山东大学齐鲁医院中医科,250012
摘    要:目的:观察脑心通胶囊对代谢综合征(MS)患者左心室重量、功能特征的影响。方法:选择60例MS患者,应用多普勒超声检测心脏左室结构及功能,根据有无高血压分为MS组、高血压代谢综合征(HMS)组,对比两组左室结构、功能的异同,并对HMS组给予脑心通胶囊治疗,观察其对左室肥厚及功能的影响。结果:与MS组及对照组比较,HMS组的左室后壁厚度、室间隔厚度、左室重量显著增大,舒张早期与舒张晚期峰值流速的比值(E/A)显著减小,差异有显著性(P〈0.01);治疗后HMS组左室重量、E/A与治疗前比较差异亦有显著性(P〈0.01)。结论:MS患者多有左室结构和功能的损害,脑心通胶囊可减缓、逆转左室肥厚,从而改善心脏功能。

关 键 词:代谢性综合征/并发症  心室功能  左/中医药疗法  @脑心通胶囊
收稿时间:07 11 2005 12:00AM
修稿时间:2005-07-112005-11-02

Effects of Naoxintong Capsules on Left Ventricular Hypertrophy in Patients of Metabolic Syndrome
Liu Yunfang, Zhao Yuxia, Yu Huiming,et al..Effects of Naoxintong Capsules on Left Ventricular Hypertrophy in Patients of Metabolic Syndrome[J].Journal of Traditional Chinese Medicine,2006,47(8):594-595.
Authors:Liu Yunfang  Zhao Yuxia  Yu Huiming  
Institution:Qilu Hospital of Shandong University,Jinan 250012
Abstract:Objective:To observe effects of Naoxintong Capsules on left ventricular weight and functional characteristics in the patient of metabolic syndrome(MS).Methods:Left ventricular structures and function were detected with Duppler ultrasonic examination.Sixty cases of MS were divided into MS group(without hypertension) and hypertesion MS (HMS) group(with hypertension) and left ventricular structures and functions were compared between groups.Effects of Naoxintong Capsules on left ventricular hypertrophy and function in the HMS group were investigated.Results:Compared with MS group and the control group,thickness of the left ventricular posterior wall,thickness of the interventricular septum and left ventricular weight significantly increased,and E/A value significantly decreased (P<0.01) in the HMS group.There were significant differences in left ventricular weight and E/A in the HMS group(P<0.01) before and after treatment.Conclusion:Most MS patients have changes of left ventricular structures and functions,and Naoxintong Capsules can alleviate and reverse left ventricular hypertrophy,so as to improve function of the heart.
Keywords:Metabolic syndrome/complication  Ventricular function  left/TCM therapy  @Naoxintong Capsules
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