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胃癌的自体荧光图像分析
引用本文:萧树东,钟喨,罗鸿仔,陈晓宇,施尧,郭强苏.胃癌的自体荧光图像分析[J].胃肠病学,2002,7(1):11-13.
作者姓名:萧树东  钟喨  罗鸿仔  陈晓宇  施尧  郭强苏
作者单位:1. 上海第二医科大学附属仁济医院上海市消化疾病研究所,200001
2. 上海第二医科大学附属仁济医院上海市消化疾病研究所放射科,200001
3. 上海第二医科大学组胚教研室
摘    要:目的:探讨胃癌组织显微自体荧光图像的特征表现。方法:采用氩离子(Ar^ )激光(激发波长488nm)和氦氖(He-Ne)激光(激发波长543nm)的双通道法激光扫描共聚焦显微镜对16例胃癌手术标本进行自体荧光图像分析,并作自身对照研究。结论:胃正常组织各层的显微自体荧光图像均以绿色荧光为主,胃癌的显微自体荧光图像则红色荧光强度明显增加,并可见棕红色区,其显示率达100%。结论:棕红色区是胃癌在显微自体荧光图像上的特征表现,自体荧光图像分析是胃癌诊断的有效方法。

关 键 词:胃肿瘤  自体荧光图像  激光扫描共聚值显微镜
修稿时间:2001年8月10日

Autofluorescence Imaging Analysis of Gastric Cancer
XIAO Shudong,ZHONG Liang,LUO Hongyu,CHEN Xiaoyu,SHI Yao,GUO Qiangsu.Autofluorescence Imaging Analysis of Gastric Cancer[J].Chinese Journal of Gastroenterology,2002,7(1):11-13.
Authors:XIAO Shudong  ZHONG Liang  LUO Hongyu  CHEN Xiaoyu  SHI Yao  GUO Qiangsu
Institution:XIAO Shudong,ZHONG Liang,LUO Hongyu,CHEN Xiaoyu,SHI Yao,GUO Qiangsu. Shanghai Second Medical University Renji Hospital,Shanghai Institute of Digestive Disease,Shanghai
Abstract:Background/Aims: To investigate the characteristics of autofluorescence image in gastric can- cer. Methods: A double-channel laser scanning confocal microscopy with Argon ion laser(excitation wavelength 488 nm) and Helium-Neon laser(excitation wavelength 543 nm) were used to detect the autofluorescence from 16 surgical specimens of gastric cancer and corresponding normal tissue. Re- sults: Autofluorescence emitted from normal gastric tissue appeared as a green image. The intensity of red color increased obviously in all gastric cancer tissue(100%) after illuminatin and it appeared as a brown reddish image. Conclusions: Brown reddish image is the characteristics of autofluorescence in gastric cancer excited by Argon ion laser and Helium-Neon laser with a double-channel laser scanning confocal microscope. Autofluorescence imaging analysis is useful in the diagnosis of gastric cancer.
Keywords:Stomach Neoplasms  Fluorescence  Microscopy  Confocal  
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