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Solriamfetol for the Treatment of Excessive Sleepiness in OSA: A Placebo-Controlled Randomized Withdrawal Study
Authors:Patrick J Strollo  Jan Hedner  Nancy Collop  Daniel G Lorch  Dan Chen  Lawrence P Carter  Yuan Lu  Lawrence Lee  Jed Black  Jean-Louis Pépin  Susan Redline
Institution:1. From the University of Pittsburgh/Veterans Administration Pittsburgh Health System, Pittsburgh, PA;2. Sahlgrenska University Hospital, Gothenberg University, Gothenberg, Sweden;3. Emory Sleep Center, Emory University, Atlanta, GA;4. PAB Clinical Research/Florida Sleep Disorder Center, Brandon, FL;5. Jazz Pharmaceuticals plc, Palo Alto, CA;6. University of Arkansas for Medical Sciences, Little Rock, AR;7. Stanford University Center for Sleep Sciences and Medicine, Redwood City, CA;8. INSERM U1042, Grenoble Alpes University Hospital, Grenoble, France;9. Brigham and Women’s Hospital and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
Abstract:
Keywords:excessive sleepiness  JZP-110  obstructive sleep apnea  OSA  solriamfetol  TONES 4  CGI-C  Clinical Global Impression of Change  ES  excessive sleepiness  ESS  Epworth Sleepiness Scale  FOSQ-10  10-item Functional Outcomes of Sleep Questionnaire  LS  least squares  mITT  modified intention to treat  MWT  Maintenance of Wakefulness Test  PGI-C  Patient Global Impression of Change
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