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同系异体大鼠子宫原位移植的实验研究
引用本文:严沁,吴晓梅,何晓英,席晓薇,杨懿霞,万小平.同系异体大鼠子宫原位移植的实验研究[J].山东医药,2009,49(26):10-11.
作者姓名:严沁  吴晓梅  何晓英  席晓薇  杨懿霞  万小平
作者单位:上海交通大学附属第一人民医院,上海,200080
基金项目:上海市科学技术委员会科研计划基金资助项目,上海市卫生局青年科研基金资助项目 
摘    要:目的建立同系异体大鼠子宫原位移植实验模型。方法8—10周龄近交系雌性Wistar大鼠120只,进行同系异体子宫原位移植,术后3周观察移植子宫成活情况。结果共实施60例同系异体大鼠子宫原位移植手术,手术成功53例、失败7例;53例手术成功者47例移植子宫成活、6例坏死,移植子宫成活率88.7%。结论同系异体大鼠子宫原位移植模型的建立是可行的,可作为子宫移植基础研究的技术平台。

关 键 词:大鼠  子宫  器官移植  子宫移植

Study on orthotopic uterine transplantation in syngenic rat
YAN Qin,WU Xiao-mei,HE Xiao-ying,XI Xiao-wei,YANG Yi-xia,WAN Xiao-ping.Study on orthotopic uterine transplantation in syngenic rat[J].Shandong Medical Journal,2009,49(26):10-11.
Authors:YAN Qin  WU Xiao-mei  HE Xiao-ying  XI Xiao-wei  YANG Yi-xia  WAN Xiao-ping
Institution:( The First People's Hospital, Shanghai Jiao Tong University, Shanghai 200080 ,P. R. China)
Abstract:Objection To establish the animal model of orthotopie allograft uterine transplantation in rat. Methods The orthotopic transplantations were conducted in 120 aged 10-12 weeks inbred female Wistar rats. After 3 weeks, the survival situation of transplanted uterus were observed. Results 60 orthotopie uterine transplantation were practised, 53 cases succeeded and 7 failed. Among the 53 living reciplem rats, 47 transplanted uteri were viable. The viable rate of uterine transplantation was 88.7%. Conclusion It is feasible to establish the model of orthotopie uterine transplantation in syngenie rat, which should be feasibility for further experimental study of uterine transplantation.
Keywords:rat  uterus  organ transplantation  uterine transplantation
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