Effects of pioglitazone on arteriosclerotic-related factors and short term prognosis in patients with coronary disease and diabetes |
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| Authors: | MEI Bai-qiang LIANG Qian YANG Xi-li OU Zhan-peng WEN Yong-zhao |
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| Institution: | MEI Bai-qiang1,LIANG Qian,YANG Xi-li,OU Zhan-peng2,WEN Yong-zhao3 1. Department of Cardiology,The First People's Hospital of Foshan,Foshan Guangdong 528000,China 2. Stomatology Hospital,Li-wan District,Guangzhou 510170,China 3. Department of pediatrics,Maternal and Child Health Hospital of Foshan,China |
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| Abstract: | Background Thiazolidinediones (TZDs) not only improve insulin resistance, lowering blood sugar, also has anti-atherosclerotic effect. However, whether the protective effect on cardiovascular pioglitazone is still controversial. Methods Totally 98 patients with coronary disease and diabetes mellitus were randomly divided into pioglitazone group (n = 48) receiving conventional therapy and pioglitazone (15 mg/day), and control group (n = 50) merely receiving conventional therapy. The patients were followed up ... |
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| Keywords: | pioglitazone plasminogen activator Inhibitor 1 P-selectin coronary disease diabetes mellitus |
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