| 重组组织型纤溶酶原激活剂治疗急性心肌梗塞42例临床分析 |
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| 引用本文： | 陈国伟,潘永康,李兆文,杨柯,李婺芳,袁贤奇,龙凤军,郭有方.重组组织型纤溶酶原激活剂治疗急性心肌梗塞42例临床分析[J].中国循环杂志,1994(1). |
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| 作者姓名： | 陈国伟 潘永康 李兆文 杨柯 李婺芳 袁贤奇 龙凤军 郭有方 |
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| 作者单位： | 澳门镜湖医院监护病室，广州中山医科大学第一附属医院心内科，北京中国医学科学院阜外医院内科 |
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| 摘 要： | 本文报道应用重组组织型纤溶酶原激活剂（ｒｔ－ＰＡ）治疗４２例急性心肌梗塞，对其临床效果进行分析，证实ｒｔ－ＰＡ有缩小梗塞范围，改善心功能，提高患者生活质量和降低病死率的作用。在用药过程中。本组病例未见到严重出血及其他严重副作用。作者对ｒｔ－ＰＡ的给药时机、应用指征及禁忌证作了探讨。
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| 关 键 词： | 急性心肌梗塞，重组组织型纤溶酶原激活剂，溶血栓疗法 |
USE OF RECOMBINANT TISSUE-TYPE PLASMINOGEN ACTIVATOR IN THE TREATMENT OF ACUTE MYOCARDIAL INFARCTION: A CLINICAL ANALYSIS OF 42 PATIENTS. |
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| Chen Guo-Wei,Pan Yong-Kang, Li Zhao-Wen,et al..USE OF RECOMBINANT TISSUE-TYPE PLASMINOGEN ACTIVATOR IN THE TREATMENT OF ACUTE MYOCARDIAL INFARCTION: A CLINICAL ANALYSIS OF 42 PATIENTS.[J].Chinese Circulation Journal,1994(1). |
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| Authors: | Chen Guo-Wei Pan Yong-Kang Li Zhao-Wen |
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| Institution: | Intensive Care Unit; Kiang Wu Hospital; Macau. |
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| Abstract: | The use of recombinant tissue-type plasminogen activator (rt-PA) in the treatment of 42 Patients of acute myocardial infarction was reported. The clinical effects of rt-PA were analysed. The use of rt-PA could: 1. decrease the size of myocardial infarction; 2.improve left ventricular function; 3. improve live quality, and 4. reduce mortality. No serious hemorrhage or other serious side effects were found during the treatment. Appropriate time of administration, indication and contraindication of rt-PA were discussed. |
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| Keywords: | Acute myocardial infarction (AMI) Recombinant tissue-type plasminogen activator (rt-PA) Thrombolytic therapy |
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