| 疏血通注射液对2型糖尿病患者炎性因子的影响 |
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| 引用本文： | 高建苑,吴立平,张荣怀,韩亚军,房海英,陈金凤.疏血通注射液对2型糖尿病患者炎性因子的影响[J].中西医结合心脑血管病杂志,2012,10(1):21-22. |
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| 作者姓名： | 高建苑 吴立平 张荣怀 韩亚军 房海英 陈金凤 |
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| 作者单位： | 第四军医大学第一附属医院,710032 |
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| 基金项目： | 2008年陕西省科技发展计划基金项目(No.2008K16-G10)(1) |
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| 摘 要： | 目的观察疏血通注射液对2型糖尿病患者炎性细胞因子影响。方法 175例2型糖尿病患者随机分为对照组和治疗组,分别给予双胍类和双胍类基础上加疏血通注射液。入选后第2天和第16天分别测定肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)、C反应蛋白、纤溶酶原激活抑制物-1(PAI-1)和脂联素。结果治疗16d后,治疗组TNF-α、IL-6、C反应蛋白、PAI-1和脂联素与对照组显著差异(P<0.05)。结论疏血通注射液对2型糖尿病患者炎性细胞因子调节有一定效果。
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| 关 键 词： | 2型糖尿病 疏血通注射液 炎性因子 胰岛素抵抗 水蛭素 |
Effect of Shuxuetong Injection on Inflammatory Factors in Type 2 Diabetes Mellitus |
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| Institution: | Gao Jianyuan,Wu Liping,Zhang Ronghuai,et alThe First Affiliated Hospital,The Fourth Military Medical University of PLA(Xi’an 710032) |
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| Abstract: | Objective To observe the effect of Shuxuetong injection on inflammatory factors in patients(pts) with type 2 diabetes mellitus.Methods One hundred and seventy-five patients with type 2 diabetes mellitus were randomly assigned to control group treated with metformin,and therapy group treated with Shuxuetong injection and metformin.Tumor necrosis factor-α(TNF-α),inter leukin-6(IL-6),C-reactive protein(CRP),plasminogen activator inhibitor-1(PAI-1) and adiponectin were examined at day 2 and day 16.Results There are significant differences in TNF-α,IL-6,CRP,PAI-1,and adiponectin between therapy group and control group at day 16(P<0.05).Conclusion Shuxuetong injection is effective for regulations of inflammatory factors in pts with type 2 diabetes mellitus. |
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| Keywords: | type 2 diabetes mellitus Shuxuetong Injection inflammatory factors insulin resistance hirudin |
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