| 疫苗诱导的免疫性血栓性血小板减少症的可能机制与研究进展 |
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| 引用本文： | 朱耐伟,张 昕,霍丹丹,吴 丹,聂为民,黄 磊. 疫苗诱导的免疫性血栓性血小板减少症的可能机制与研究进展[J]. 传染病信息, 2021, 34(4): 296-300. DOI: 10.3969/j.issn.1007-8134.2021.04.003 |
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| 作者姓名： | 朱耐伟 张 昕 霍丹丹 吴 丹 聂为民 黄 磊 |
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| 作者单位： | 100039 北京,解放军总医院第五医学中心感染病医学部感染性疾病科 |
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| 基金项目： | 国家自然科学基金面上项目（81772185） |
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| 摘 要： | 2019年底至今,严重急性呼吸综合征冠状病毒-2(severe acute respiratory syndrome coronavirus-2,SARS-CoV-2)引起的新型冠状病毒肺炎在全球范围内广泛传播,严重威胁着人类的生命安全.目前,尚无针对SARS-CoV-2的特效抗病毒药物,疫苗接种成为最有效且经济的防控...
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| 关 键 词： | 严重急性呼吸综合征冠状病毒-2 新型冠状病毒肺炎 疫苗 疫苗诱导的免疫性血栓性血小板减少症 机制 |
Possible mechanism and research progress of vaccine-induced immune thrombotic thrombocytopenia |
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| ZHU Nai-wei,ZHANG Xin,HUO Dan-dan,WU Dan,NIE Wei-min,HUANG Lei. Possible mechanism and research progress of vaccine-induced immune thrombotic thrombocytopenia[J]. Infectious Disease Information, 2021, 34(4): 296-300. DOI: 10.3969/j.issn.1007-8134.2021.04.003 |
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| Authors: | ZHU Nai-wei ZHANG Xin HUO Dan-dan WU Dan NIE Wei-min HUANG Lei |
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| Abstract: | Since the end of 2019, coronavirus disease-2019 caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been widely spread worldwide, and seriously threatened human health. At present, no specific antiviral drugs are available for SARS-CoV-2. Vaccination has become the most effective and economic means of prevention and control. As the large amounts of vaccination and subsequent follow-ups commence, vaccine-related spontaneous heparin-induced thrombocytopenia, namely vaccine-induced immune thrombotic thrombocytopenia (VITT) has gradually emerged in clinical practice. This paper reviews the possible mechanism and research progress of VITT. |
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| Keywords: | SARS-CoV-2 COVID-19 vaccine vaccine-induced immune thrombotic thrombocytopenia mechanism |
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