| 关注ACE2的心血管保护作用 |
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| 引用本文： | 于诗然,杨旻,曹新冉,朱桂月,甘立军,董波.关注ACE2的心血管保护作用[J].中国动脉硬化杂志,2018,26(5):433-437. |
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| 作者姓名： | 于诗然 杨旻 曹新冉 朱桂月 甘立军 董波 |
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| 作者单位： | 山东大学附属省立医院心内科;青海红十字医院心内科 |
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| 基金项目： | 国家自然科学基金面上项目(81170207,81570729) |
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| 摘 要： | 血管紧张素转换酶2(ACE2)是肾素-血管紧张素系统(RAS)的新成员,目前认为其与动脉粥样硬化、动脉瘤、冠心病心肌梗死、糖尿病心肌病(DCM)及阿霉素心肌病(ACM)的过程密切相关。ACE2具有抑制血管重构及心肌重构的作用,在以上疾病的预防及治疗中具有重要意义。
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| 关 键 词： | 血管紧张素转换酶2 动脉粥样硬化 动脉瘤 心肌重构 |
| 收稿时间： | 2018/1/20 0:00:00 |
| 修稿时间： | 2018/3/10 0:00:00 |
Focus on the effects of ACE2 on cardiovascular protection |
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| YU Shi-Ran,YANG Min,CAO Xin-Ran,ZHU Gui-Yue,GAN Li-Jun and DONG-Bo.Focus on the effects of ACE2 on cardiovascular protection[J].Chinese Journal of Arteriosclerosis,2018,26(5):433-437. |
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| Authors: | YU Shi-Ran YANG Min CAO Xin-Ran ZHU Gui-Yue GAN Li-Jun and DONG-Bo |
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| Institution: | Department of Cardiology, the Affiliated Provincial Hospital of Shandong University, Jinan, Shandong 250021,Department of Cardiology, the Affiliated Provincial Hospital of Shandong University, Jinan, Shandong 250021,Department of Cardiology, the Affiliated Provincial Hospital of Shandong University, Jinan, Shandong 250021,Department of Cardiology, the Affiliated Provincial Hospital of Shandong University, Jinan, Shandong 250021,Department of Cardiology, Qinghai Red Cross Hospital, Xining, Qinghai 810000, China and Department of Cardiology, the Affiliated Provincial Hospital of Shandong University, Jinan, Shandong 250021;Department of Cardiology, Qinghai Red Cross Hospital, Xining, Qinghai 810000, China |
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| Abstract: | Recent studies have shown that angiotensin-converting enzyme-2 (ACE2) plays an important role in the pathogenesis of atherosclerosis, aneurysm, coronary heart disease, diabetic cardiomyopathy and adriamycin cardiomyopathy. There is increasing support for the belief that ACE2 has a significant role in inhibiting vascular and myocardial remodeling, which is of great significance in the prevention and treatment of cardiovascular diseases. |
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| Keywords: | Angiotensin-converting enzyme-2 Atherosclerosis Aneurysm Myocardial remodeling |
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