| 氧化型低密度脂蛋白、单核细胞趋化蛋白1与脑梗死颈动脉粥样硬化的关系 |
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| 引用本文： | 李世英,李峥,张晋霞,贺永贵,张文彦,刘斌,刘昊.氧化型低密度脂蛋白、单核细胞趋化蛋白1与脑梗死颈动脉粥样硬化的关系[J].中国动脉硬化杂志,2016,24(5):495-498. |
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| 作者姓名： | 李世英 李峥 张晋霞 贺永贵 张文彦 刘斌 刘昊 |
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| 作者单位： | 华北理工大学附属医院神经内科,河北省唐山市 063000;河北省玉田县医院神经内科,河北省玉田县 064100;华北理工大学附属医院神经内科,河北省唐山市 063000;华北理工大学附属医院神经内科,河北省唐山市 063000;华北理工大学附属医院神经内科,河北省唐山市 063000;华北理工大学附属医院神经内科,河北省唐山市 063000;华北理工大学附属医院神经内科,河北省唐山市 063000 |
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| 基金项目： | 河北省科技厅科技计划项目(122777103)；唐山市科技局课题(12150220B-4) |
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| 摘 要： | 目的探讨血清氧化型低密度脂蛋白(ox-LDL)、单核细胞趋化蛋白1(MCP-1)水平与脑梗死颈动脉粥样硬化(CAS)的关系。方法选取112例急性前循环脑梗死患者为脑梗死组,49例健康体检者为对照组,均行颈动脉超声检查。脑梗死组按颈动脉内膜中膜厚度(IMT)分为IMT正常组、IMT增厚组及斑块组;其中斑块组按斑块回声性质分为强回声斑块组、混合回声斑块组及低回声斑块组。比较脑梗死组与对照组、不同类型脑梗死亚组血清ox-LDL、MCP-1的水平。结果脑梗死组血清ox-LDL、MCP-1水平高于对照组,斑块组血清ox-LDL、MCP-1水平高于IMT正常组、IMT增厚组,低回声斑块组血清ox-LDL、MCP-1水平高于强回声斑块组、混合回声斑块组,差异均有统计学意义(P0.05)。结论脑梗死患者血清ox-LDL、MCP-1水平越高,CAS程度越重,斑块发生率越高,且以低回声斑块居多。
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| 关 键 词： | 氧化型低密度脂蛋白 单核细胞趋化蛋白1 脑梗死 颈动脉粥样硬化 |
| 收稿时间： | 2016/1/21 0:00:00 |
| 修稿时间： | 2016/3/10 0:00:00 |
The Relationship Between Oxidized Low Density Lipoprotein, Monocyte Chemotactic Protein-1 and Carotid Atherosclerosis in Patients with Cerebral Infarction |
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| LI Shi-Ying,LI Zheng,ZHANG Jin-Xi,HE Yong-Gui,ZHANG Wen-Yan,LIU Bin and LIU Hao.The Relationship Between Oxidized Low Density Lipoprotein, Monocyte Chemotactic Protein-1 and Carotid Atherosclerosis in Patients with Cerebral Infarction[J].Chinese Journal of Arteriosclerosis,2016,24(5):495-498. |
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| Authors: | LI Shi-Ying LI Zheng ZHANG Jin-Xi HE Yong-Gui ZHANG Wen-Yan LIU Bin and LIU Hao |
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| Institution: | Department of Neurology, the Affiliated Hospital, North China University of Science and Technology, Tangshan, Hebei 063000, China;Department of Neurology, Yutian County Hospital of Hebei Province, Yutian, Hebei 064100, China;Department of Neurology, the Affiliated Hospital, North China University of Science and Technology, Tangshan, Hebei 063000, China;Department of Neurology, the Affiliated Hospital, North China University of Science and Technology, Tangshan, Hebei 063000, China;Department of Neurology, the Affiliated Hospital, North China University of Science and Technology, Tangshan, Hebei 063000, China;Department of Neurology, the Affiliated Hospital, North China University of Science and Technology, Tangshan, Hebei 063000, China;Department of Neurology, the Affiliated Hospital, North China University of Science and Technology, Tangshan, Hebei 063000, China |
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| Abstract: | |
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| Keywords: | Oxidized Low Density Lipoprotein Monocyte Chemotactic Protein-1 Cerebral Infarction Carotid Atherosclerosis |
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