早发冠心病的危险因素及其冠状动脉病变特点

目的 探讨早发冠心病惠者的冠状动脉病变特点及其相关危险因素.方法 294例经冠状动脉造影确诊的冠心病患者,根据年龄分为早发冠心痛组(男性<55岁,女性<65岁)169例和老年冠心病组125例.对两组患者的相关临床资料进行回顾性统计分析,比较二者的冠状动脉病变特点、血脂水平、高血压病史、糖尿病痛史、冠心病家族史、吸烟史、饮酒史等,评价其是否存在差异性.结果 早发冠心痛组吸烟、冠心病阳性家族史、血甘油三酯水平高于老年冠心病组(P<0.05),而高血压、糖尿病略低于老年冠心痛组(P>0.05).早发冠心病组患者常以急性冠状动脉综合征起病(66.3%比45.6%),冠状动脉病变多为单支病变(44.4%比22.4%),老年冠心病组以多支病变为主.结论 吸烟、冠心病阳性家族史、血甘油三酯水平升高在早发冠心病的发生发展中起重要作用,早发冠心痛以单支冠状动脉病变为主.

The Risk Factors and Clinical Features of Coronary Lesions in Patient with Premature Coronary Heart Disease

Aim To investigate the risk factors and clinical features of coronary lesions in patient with premature coronary heart disease.Methods 294 patients with coronary heart disease(CHD)were divided into premature CHD group(male<55 years old,n= 104; female<65 years old,n=65)and aged CHD group(male≥55 years old,n=74; female≥65 years old,n = 51).The risk factors of premature CHD and the features of coronary lesions were illustrated.Results The percentage of smoking,triglyceride(TG)level and family history in patients with premature CHD were higher than those in patients with aged CHD(P<0.05).But the patients with premature CHD had lower rate of hyper-tension and diabetes compared with the patients with aged CHD(P>0.05).There were significantly more premature CHD patients with acute coronary syndrome(66.3%vs 45.6%,P<0.05),more premature CHD patients had single ves-sel lesion(P<0.05),lower average lesion score(P<0.05).Conclusion Smoking,family history,increased TG level might play an important role in the development of premature coronary heart disease.