原发性甲状腺功能减退致类多肌炎样综合征四例报道并文献复习

目的 提高甲状腺功能减退致类多肌炎样综合征的认识.方法 报道4例确诊为原发性甲状腺功能减退致类多肌炎样综合征的临床特点.结果 4例患者均为男性,开始均出现双下肢乏力和肌酸激酶明显增高等类多肌炎样表现,后检查确诊为原发性甲状腺功能减退,经过甲状腺激素补充治疗后类多肌炎样表现明显好转.结论 甲状腺功能减退可合并类多肌炎样综合征,临床上肌酸激酶增高时应注意筛杳甲状腺功能.

Primary hypothyroidism associated with polymyositis-like syndrome:four cases report and review of literature

Objective To understand the pathogenesis of primary hypothyroidism associated with polymyositis-like syndrome.Method Four cases were presented and the clinical characteristics were analyzed.Results All of the four patients were male.Complaints of weakness primarily affecting proximal muscles and elevation of muscle enzymes were presented.Primary hypothyroidism was diagnosed after clinical examination.Complaints of weakness and the elevated muscle enzymes were all improved after the substitution of thyroxine.Conclusion Hypothyroidism could cause polymyositis-like syndrome,and thyroid function should be screened when elevation of muscle enzymes is presented.