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Hepatic NFAT signaling regulates the expression of inflammatory cytokines in cholestasis
Authors:Shi-Ying Cai  Dongke Yu  Carol J Soroka  Jing Wang  James L Boyer
Institution:1. Departments of Internal and Experimental Vascular Medicine, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands;2. Department of Surgery, Spaarne Hospital, Hoofddorp, The Netherlands;1. Division of GI/Hepatology, University of California, San Francisco;2. Department of Surgery, University of California, San Francisco;3. Department of Obstetrics and Gynecology, University of California, San Francisco;1. Barcelona Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clínic, IDIBAPS, University of Barcelona, Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN-Liver), Barcelona, Spain;2. Division of Gastroenterology, Azienda Ospedaliero-Universitaria di Modena and University of Modena and Reggio Emilia, Modena, Italy;3. PhD Program in Clinical and Experimental Medicine, University of Modena and Reggio Emilia, Modena, Italy;4. Centro de Investigación Biomédica Red de Enfermedades Hepáticas y Digestivas (CIBEREHD);1. I. Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany;2. European Reference Network on Hepatological Diseases (ERN RARE-LIVER);3. Department of Clinical Science, University of Bergen, Bergen, Norway;4. Norwegian PSC Research Centre, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway
Abstract:
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  • Keywords:Bile acids  Nuclear factor of activated T-cells  Inflammatory cytokines  Cholestatic liver injury
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