广西和贵州部分美沙酮维持治疗门诊服药人员HIVHCV梅毒及HSV-2感染状况

目的了解广西、贵州美沙酮维持治疗（MMT）门诊服药人员中,艾滋病病毒（HIV）、丙型肝炎病毒（HCV）、梅毒螺旋体（TP）及单纯疱疹病毒Ⅱ型（HSV-2）的感染情况。方法对两省（自治区）艾滋病疫情较重地区的16个美沙酮门诊的1 678名服药人员进行问卷调查,同时检测抗-HIV抗体、抗-HCV抗体、梅毒抗体,并对HIV抗体阳性者检测HSV-2抗体。结果 1 652人中,抗-HIV、抗-HCV及梅毒抗体的阳性率分别为26.63%（440/1 652）、83.36%（1 377/1 652）和5.08%（84/1 652）。440例HIV阳性者中,433人检测了HSV-2,HSV-2抗体阳性率为57.27%（248/433）。结论被调查人群中,HIV、HCV、梅毒感染率均高,而且抗-HIV阳性者中,HSV-2感染率很高,应加强对该人群的管理和服务,以防止这些疾病进一步蔓延。

A survey of HIV,HCV, syphilis and HSV-2 among drug users attending methadone maintenance treatment clinics in Guangxi and Guizhou.

Objective To study HIV,HCV,syphilis and HSV-2 infections among drug users attending methadone maintenance treatment clinics in Guangxi and Guizhou.Methods A total of 1678 drug users attending methadone maintenance treatment（MMT） clinics were interviewed with questionnaire and their blood specimen were collected for detecting antibodies against HIV,HCV and syphilis.For HIV-positive individuals,antibody against HSV-2 was detected.The prevalence was calculated for each specific disease and for co-infections.Results The prevalence of HIV,HCV and syphilis was 26.63%（440/1652）,83.36%（1377/1652）,and 5.08%（84/1652）,respectively.The co-infection of HIV and HSV-2 was 57.27%（248/433）.Conclusion Drug users at MMT clinics had a high prevalence of HIV,HCV and syphilis.Management and service should be strengthened for this specific group of population so as to prevent further spreading of these diseases.