动脉僵硬度对介入治疗患者的危险分层及预后评价

目的探讨动脉僵硬度对PCI患者的危险分层和预后评价。方法选择冠心病并行PCI的患者316例,均进行颈-股脉搏波传导速度(cfPWV)检测评价动脉僵硬度。根据cfPWV水平将患者分为3组,Ⅰ组67例(cfPWV0-10.0 m/s),Ⅱ组98例(cfPWV)0.1-13.0 m/s),Ⅲ组151例(cfPWV>13.0 m/s)。记录患者临床特征、术后并发症和随访主要心血管事件(MACE)发生率,并行相关分析。结果与Ⅰ组和Ⅱ组比较,Ⅲ组年龄偏大,糖尿病、心肌梗死和高血压所占比例多,C型病变和3支病变多见(p<0.05)。术后并发症发生率、远期非致死性心肌梗死和血运重建发生率显著增加(P<0.05)。cfPWV与MACE发生呈正相关(OP=1.98,95%CI:1.039-3.770)。结论 cfPwV与冠状动脉病变的严重程度及PCI后远期MACE发生率增加密切相关。

The value of arterial stiffness in risk stratification and outcome evaluation in patients receiving percutaneous coronary intervention

Objective To investigate the value of arterial stiffness in risk stratification and outcome evaluation in patients receiving PCI. Methods 316 consecutive patients who received PCI were studied. Carotid-femoral pulse wave velocity(cfPWV) was measured to evaluate large artery stiffness. According to cfPWV they were divided into 3 groups:group Ⅰ (cfPWV 0-10. 0 m/s,67 patients), group Ⅱ(cfPWV 10.1-13.0 m/s,98 patients),group Ⅲ(cfPWV>13. 0 m/s,151 patients). The clinical characteristics and main adverse cardiac events(MACE) during follow-up period were analyzed. Results The percentages of old patients,diabetes, hypertension,myocardial infarction, type C lesion, and three-artery lesions were higher in group Ⅲ compared with other two groups (P<0. 05). The incidences of complications, long-term non-fatal myocardial infarction and revascularization were significantly higher in group Ⅲ than those in groups Ⅰ and Ⅱ (P