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二巯基丙磺酸钠解救急性四次甲基二砜四胺中毒的临床观察
引用本文:应斌宇,陈振洲,陈志康.二巯基丙磺酸钠解救急性四次甲基二砜四胺中毒的临床观察[J].中华内科杂志,2000,39(2):100-102.
作者姓名:应斌宇  陈振洲  陈志康
作者单位:应斌宇(325027 浙江省温州医学院附属第二医院急诊科)      张素勤(325027 浙江省温州医学院附属第二医院急诊科)      林巍(325027 浙江省温州医学院附属第二医院急诊科)      陈振洲(温州市公安局毒理实验室)      陈志康(温州医学院药理教研室)

摘    要:目的 探索急性毒鼠强(四次甲基二砜安)中毒(ATI)的临床特效解毒方法。方法 应用二巯基丙磺酸钠(Na-DMPS)解救ATI11例(次)患者进行疗效总结,并与既往常规治疗的5例患者进行比较。结果 治疗组获得满意疗效;无一例死亡,预后佳,Na-DMPS解毒作用显著;而对照组5例死亡4例,1例遗留有严重痴呆症。结论 Na-DMPS对ATI具有特效解毒作用,值得临床推广应用。

关 键 词:二巯基丙磺酸钠  鼠药中毒  毒鼠强  急救
修稿时间:1999-07-29

A clinical study on Na-DMPS in the emergency treatment of acute tetramine intoxication
YING Binyu,CHEN Zhenzhou,CHEN Zhikang,et al.A clinical study on Na-DMPS in the emergency treatment of acute tetramine intoxication[J].Chinese Journal of Internal Medicine,2000,39(2):100-102.
Authors:YING Binyu  CHEN Zhenzhou  CHEN Zhikang  
Institution:YING Binyu,CHEN Zhenzhou,CHEN Zhikang,et al Department of Emergency,The Second Affliated Hospital,Wenzhou Medical College,Wenzhou 325027,China
Abstract:Objective To find the clinical specific antidotal treatment of acute tetramine intexication (ATI) Methods The therapeutic effects of sodium dimercaptopropan (Na DMPS) were observed in 11 ATI patients and the results were compared with those of 5 cases treated with traditional methods Results All the cases treated with Na DMPS got good outcome and no case died, while 4 cases in the control group died and in the remaining one severe dementia was left over Conclusion It is suggested that Na DMPS may be a specific remedy for ATI and the therapeutic effects are reliable clinically
Keywords:Poisoning  Unithiol  Antidotes
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