| 心脏端粒酶的研究概况 |
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| 引用本文： | 常连生,郭志坤.心脏端粒酶的研究概况[J].心血管病学进展,2005,26(5):547-550. |
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| 作者姓名： | 常连生 郭志坤 |
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| 作者单位： | 新乡医学院心脏形态学研究室,河南,新乡,453003 |
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| 基金项目： | 河南省自然科学基金项目(412000900) |
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| 摘 要： | 端粒长度、端粒酶活性在心血管疾病发生发展过程中的变化引起了心血管界的关注。现就端粒酶在正常心脏中的表达及活性的变化,端粒酶与心肌细胞损伤、冠状动脉粥样硬化、心力衰竭等心血管疾病之间的关系和检测心脏端粒长度和端粒酶活性的技术和方法作一综述。
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| 关 键 词： | 端粒 端粒酶 心血管疾病 心肌细胞损伤 冠状动脉粥样硬化 心力衰竭 |
| 文章编号： | 1004-3934(2005)05-0547-04 |
| 收稿时间： | 2005-02-02 |
| 修稿时间： | 2005-04-26 |
Research of Cardiac Telomerase |
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| CHANG Lian-sheng,GUO Zhi-kun.Research of Cardiac Telomerase[J].Advances in Cardiovascular Diseases,2005,26(5):547-550. |
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| Authors: | CHANG Lian-sheng GUO Zhi-kun |
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| Institution: | ZengShu;ShenJiao |
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| Abstract: | It arouses attention in cardiovascular field that the changes of telomere length and telomerase activity during occurrence and development of cardiovascular diseases.The review summarized the changes of telomerase expression and activity in normal heart,the relation between telomerase and cardiovascular diseases such as injured myocardium,coronal atherosclerosis,heart failure and so on,and the technologies and methods of measuring telomere length and telomerase activity in the heart. |
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| Keywords: | Telomere Telomerase Cardiovascular diseases Injured myocardium Coronal atherosclerosis |
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