| 晚期糖基化终产物受体在心血管疾病中的研究进展 |
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| 引用本文： | 罗翊芝.晚期糖基化终产物受体在心血管疾病中的研究进展[J].心血管病学进展,2010,31(2):273-275. |
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| 作者姓名： | 罗翊芝 |
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| 作者单位： | 广州医学院第二附属医院心内科,广州心血管疾病研究所,广东,广州,510260 |
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| 基金项目： | 广州市属高校科技项目，广东省自然科学基金 |
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| 摘 要： | 晚期糖基化终产物受体属于细胞表面分子免疫球蛋白超家族中的一个新成员,可与多种配体结合后影响细胞内信号传导、刺激细胞因子释放等从而发挥其生物学效应。已知晚期糖基化终产物受体在糖尿病并发症、心血管疾病、神经系统疾病、肿瘤等疾病中起重要作用。现主要综述其在心血管疾病中的作用。
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| 关 键 词： | 晚期糖基化终产物受体 动脉粥样硬化 高血压 糖尿病心肌病 心力衰竭 |
Influence of Receptors for Advanced Glycation Endproducts on Cardiovadcular Disease |
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| LUO Yi-zhi.Influence of Receptors for Advanced Glycation Endproducts on Cardiovadcular Disease[J].Advances in Cardiovascular Diseases,2010,31(2):273-275. |
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| Authors: | LUO Yi-zhi |
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| Institution: | LUO Yi-zhi, LIU Shi-ming ( Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical College, Guangzhou Institute of Cardiovascular Diseases, Guangzhou 510260, China) |
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| Abstract: | The receptor for advanced glycation endproducts is a member of the immunoglobulin superfamily.The receptor for advanced glycation endproducts binds to multiple ligands and exerts its effects by affecting intracellular signal transduction and stimulating the secretion of cytokines.The receptor for advanced glycation endproducts plays an important role in diabetic complications,cardiovascular diseases,neurological diseases,tumors,and more.This review focuses on its influence on cardiovascular diseases. |
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| Keywords: | receptor for advanced glycation end products atherosclerosis hypertension diabetic myocardiopathy heart failure |
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