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前列环素类药物治疗肺动脉高压的进展
引用本文:罗显元,张维君.前列环素类药物治疗肺动脉高压的进展[J].心血管病学进展,2007,28(1):149-152.
作者姓名:罗显元  张维君
作者单位:北京市心肺血管疾病研究所,北京安贞医院心内科,北京,100029
摘    要:研究显示前列环素减少和肺动脉高压的发生有关,前列环素类药物依前列醇、曲前列环素、贝前列环素、伊洛前列腺素均能降低肺动脉压力、肺血管阻力,增加心输出量、6min步行距离,同时无明显不良反应,从而改善肺动脉高压患者的症状和预后。

关 键 词:肺动脉高压  依前列醇、曲前列环素  贝前列环素  伊洛前列腺素
文章编号:1004-3934(2007)01-0149-04
修稿时间:2006-11-06

Progress in the Use of PGI2 for Treatment of Pulmonary Arterial Hypertension
LUO Xian-yuan,ZHANG Wei-jun.Progress in the Use of PGI2 for Treatment of Pulmonary Arterial Hypertension[J].Advances in Cardiovascular Diseases,2007,28(1):149-152.
Authors:LUO Xian-yuan  ZHANG Wei-jun
Institution:Department of Cardlology,Beijing Anzhen Hospital,Beijing Institute of Heart,Lung and Blood Vessel Disease, Beijing 100029, China
Abstract:Studies have demonstrated that the lowering of PGI2 may cause pulmonary arterial hypertension. PGI2 drugs, such as epoprostenol, treprostinil, beraprost, and iloprost can decrease pulmonary arterial pressure and pulmonary vascular resistance, increase cardiac output and 6 minutes walk distance, while causing no obvious adverse reaction,so relieve symptoms and improve prognosis.
Keywords:pulmonary arterial hypertension  epoprostenol  treprostinil  beraprost  iloprost
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