丹参针对脓毒血症心肌损伤保护作用的临床研究

目的观察丹参针治疗脓毒血症心肌损伤的临床疗效。方法将60例脓毒血症合并心肌损伤的患者随机分为观察组30例和对照组30例。对照组给予常规治疗，观察组在对照组治疗基础上静滴丹参针20ml／d加5％葡萄糖100ml。治疗1周后复查两组患者的心肌损伤相关指标，并进行对比分析。结果治疗1周后，两组cTnI、cTnT、CK、CK—MB和BNP等心肌标记物及APACHEⅡ评分、MDA值、SOD值、心脏变时性功能均较治疗前有明显改善（P〈0．01），而观察组比对照组的变化更为显著（P〈0．05或P〈0．01）。结论丹参针对脓毒血症所致心肌损伤具有较好的修复作用，并可有效改善脓毒血症的预后。

Clinical studies for the protective effect of Salvia injection in sepsis patients with myocardial injury

Objective To investigate the clinical efficacy of Salvia injection for the treatment of sepsis myocardial injury. Methods 60 cases of sepsis in patients with myocardial injury were randomly divided into two groups of 30 patients and 30 patients. The control group was given conventional treatment, the observation group was given Salvia infusion treatment on the basis of the control group （20 ml/d plus 5% glucose 100 ml） for one week. After one week, the myocardial injury indicators were measured and compared. Results After a week of treatment, the cTnI, cTnT, CK, CK-MB, BNP, APACHE Ⅱ score, MDA values, SOD value were all improved than pre-treatment, and the improvement was significant in observation group than that of the control group （P〈 0.01 ）. Conclusion Salvia injection can effectively improve myocardial injury and the prognosis in sepsis-induced myocardial injury.