| 拉米夫定治疗慢性重型乙型肝炎近期临床疗效观察 |
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| 引用本文： | 陈悦,任泽久,柯昌征,刘莉,汤守斌,马德强,龚钰清,李东,朱琳. 拉米夫定治疗慢性重型乙型肝炎近期临床疗效观察[J]. 实用肝脏病杂志, 2003, 6(4): 200-201 |
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| 作者姓名： | 陈悦 任泽久 柯昌征 刘莉 汤守斌 马德强 龚钰清 李东 朱琳 |
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| 作者单位： | 442000,湖北省十堰市,郧阳医学院附属太和医院肝病研究所 |
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| 摘 要： | 目的 观察拉米夫定治疗慢性重型乙型肝炎的疗效。方法 31例患者给予拉米夫定100mg口服,每日一次,观察患者病死率、病毒量、血清病毒标志物及生化指标的改变。结果 治疗组病死率为32.2％,较对照组54.8％明显下降,病毒量明显减少,生化指标改善。结论 拉米夫定治疗慢性乙型重型肝炎似有一定的近期疗效。
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| 关 键 词： | 慢性重型乙型肝炎 拉米夫定 治疗 |
Clinical improvement of lamivudine therapy in patients with chronic severe viral hepatitis B |
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| Chen Yue,Ren Zejiu,Ke Changzhen,et al.. Clinical improvement of lamivudine therapy in patients with chronic severe viral hepatitis B[J]. Journal of Clinical Hepatology, 2003, 6(4): 200-201 |
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| Authors: | Chen Yue Ren Zejiu Ke Changzhen et al. |
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| Affiliation: | Chen Yue,Ren Zejiu,Ke Changzhen,et al . Institute of Liver Disease,Affiliated Hospital of Taihe,Xunyang Medical College,Hubei,442000 |
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| Abstract: | Objective To observe the clinical efficacy of lamivudine therapy in patients with chronic severe viral hepatitis B. 'Method Fatality rate,the change of serum HBV DNA , HBVM and biochemical index were investigated before and after 31 patients with chronic severe hepatitis B were given lamivudine 100mg daily. Results Lamivudine inhibited the replication of HBV and improved the liver function tests in patients with chronic severe viral hepatitis B .The fatality rate decreased in lamivudine group. Conclusion Lamivudine is an effective drug in curing chronic severe viral hepatitis B. |
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| Keywords: | Hepatitis B Hepatic iailure Lamivudine |
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