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血浆B型钠尿肽、超敏C-反应蛋白在急性心肌梗死中的临床应用价值
引用本文:刘发军.血浆B型钠尿肽、超敏C-反应蛋白在急性心肌梗死中的临床应用价值[J].临床内科杂志,2008,25(5):314-315.
作者姓名:刘发军
作者单位:安徽省六安市第二人民医院心内科,237000
摘    要:目的 探讨急性心肌梗死(AMI)患者血浆B型钠尿肽(BNP)、超敏C-反应蛋白(hsCRP)的变化及其临床意义.方法 选择AMI患者100例,入院后均经心脏彩色B超检查,并设对照组(60例)进行比较.使用美国博适Triage干式快速定量心肌梗死检测仪测定BNP水平,采用免疫散射比浊法检测ha-CRP水平.结果 AMI患者BNP、hs-CRP水平显著高于正常心功能对照组(P<.01).AMI患者BNP、hs-CRP水平与左心室射血分数(LWF)呈负相关(r=-0.549,P<0.01),与左心室舒张末期内经(LWDD)呈正相关(r=0.412,P<0.01).结论 血浆BNP、hsCRP水平与预后显著相关,均是独立的不良的预测因子,可用于AMI的危险分层及判断预后.

关 键 词:危险分层及预后
文章编号:1001-9057(2008)05-0314-02
修稿时间:2007年12月6日

The clinical value of BNP and hs-CRP In patients with acute myocarial infarction
LIU Fajun.The clinical value of BNP and hs-CRP In patients with acute myocarial infarction[J].Journal of Clinical Internal Medicine,2008,25(5):314-315.
Authors:LIU Fajun
Abstract:Objective To investigate the plassma levels of BNP and hs-CRP in AMI patients,and estimate its value in the risk stratification and progosis.Methods The cases were divided into two groups:AMI group(including 100 AMI patients)and control group((including 60 normal individuals).The concentration of BNP was measured by Triage detection instrument,and hs-CRP by immue nephelonretry.Results 1.The concentration BNP and hs-CRP in AMI patients were significantly eleyated than control group(P all<0.01).2.The concentration BNP and hs-CRP in AMI patients had a parallel rationship with LVEDD(r=0.412,P<0.01).but a nenative correlation with left ventricular ejection fraction(LVEF)(r=-0.549,P<0.01).Conclusion The concentration of BNP and hs-CRP can help to evaluate the risk stratification and prognosis in patients with AMI.
Keywords:BNP  hs-CRP  AMI
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