首页 | 本学科首页   官方微博 | 高级检索  
检索        

自噬与自身免疫性甲状腺疾病
引用本文:郑慧娟,魏璠,魏军平.自噬与自身免疫性甲状腺疾病[J].国际内分泌代谢杂志,2017,37(1).
作者姓名:郑慧娟  魏璠  魏军平
作者单位:中国中医科学院广安门医院内分泌科,北京,100053
基金项目:国家自然科学基金资助项目(81573961)National Natural Science Foundation of China
摘    要:自噬是细胞的一个重要生物学过程,它对维持细胞存活和自身稳态发挥重要作用.大量研究表明,自噬及其相关蛋白参与调控淋巴细胞发育和免疫应答,在多种自身免疫性疾病中发挥着重要的调控作用.近年研究发现,细胞自噬与自身免疫性甲状腺疾病的发生、发展密切相关,结合近几年自身免疫性甲状腺疾病与自噬相关的报道,对自噬形成过程中的分子调控机制、自噬与自身免疫性甲状腺疾病的关系进行综述.

关 键 词:自噬  自身免疫性甲状腺疾病  桥本甲状腺炎  Graves病

Autophagy and autoimmune thyroid disease
Zheng Huijuan,Wei Fan,Wei Junping.Autophagy and autoimmune thyroid disease[J].International JOurnal of Endocrinology and Metabolism,2017,37(1).
Authors:Zheng Huijuan  Wei Fan  Wei Junping
Abstract:Autophagy is an important biological process of cells,which plays an important role in cell survival and homeostasis.A large number of studies have indicated that autophagy and its related proteins were involved in the regulation of lymphocyte development and immune response,which play an important role in many autoimmune diseases.Recent studies have found that autophagy was closely related to the occurrence and development of autoimmune thyroid diseases.Combined with the reports of autophagy related autoimmune thyroid diseases in recent years,the molecular regulation mechanisms of autophagy and the relationship between autophagy and autoimmune thyroid diseases were reviewed.
Keywords:Autophagy  Autoimmune thyroid disease  Hashimoto's thyroiditis  Graves' disease
本文献已被 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号