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脑炎是神经内科常见急症之一。早期诊断并给予适当的治疗至关重要。自身免疫性脑炎(AE)泛指一大类由于免疫系统针对中枢神经系统抗原产生反应而导致的疾病,并且逐渐被认为是非感染因素所致可逆转性脑炎的重要原因。根据病因学及治疗方法,AE可大致分为特异性抗原(抗体)相关性AE以及非特异性抗原(或抗体)相关性AE。了解有关AE的知识,对发现新疾病及加深对现有中枢神经系统疾病免疫病理机制的理解有重要意义。

The modern concept and classification of autoimmune encephalitis

??Encephalitis is one of the common emergencies of neurology.The early diagnosis and the appropriate treatment are very important.Autoimmune encephalitis (AE) refers to a major category of diseases resulting from a reaction of the immune system against antigens of central nervous system and has been gradually considered as an important non??specific factor to cause reversible encephalitis.According to the differences in etiology and therapy??AE may be divided into specific antigen (or antibody) associated AE and non??specific antigen (antibody) associated AE.Knowing more about AE is of major significance in finding new diseases and deepening the understanding of immune pathological mechanism of central nerve system.