| 前列腺癌相关生物标志物的研究进展 |
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| 引用本文： | 周朴帆,沈瑞林,熊烈,盛涛,宋保林,王省白,陆海娟,黄涛,史汉强,邵欢,赫艳梅,王晓庭,江大为,石彦波.前列腺癌相关生物标志物的研究进展[J].中华老年多器官疾病杂志,2021,20(1):72-76. |
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| 作者姓名： | 周朴帆 沈瑞林 熊烈 盛涛 宋保林 王省白 陆海娟 黄涛 史汉强 邵欢 赫艳梅 王晓庭 江大为 石彦波 |
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| 作者单位： | 浙江中医药大学附属嘉兴中医院分子医学研究中心中心实验室;嘉兴市第二医院泌尿外科;浙江中医药大学附属嘉兴中医院泌尿外科;浙江中医药大学附属嘉兴中医院放射科;浙江中医药大学附属嘉兴中医院超声科;嘉兴市糖尿病血管病变研究重点实验室 |
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| 基金项目： | 浙江省基础公益研究计划项目(LGF18H200004);嘉兴市科技计划项目(2017BY18041)。 |
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| 摘 要： | 前列腺癌作为男性最为常见的癌症之一,严重威胁着男性的健康安全。前列腺癌在预测、诊断、预后方面都面临着诸多挑战。虽然用于指导前列腺癌的各种生物标志物具有一定的临床意义,但在单独使用时仍然显现出各自的局限性。精确诊断、防止过度活检、生物标志物联合诊断体系构建等仍然是当今前列腺癌检测的研究热点。本文分析了前列腺癌在检测中所面临的问题,并就临床上常用的前列腺癌生物标志物及其相关检测体系的研究进展进行综述。
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| 关 键 词： | 前列腺癌 生物标志物 诊断 |
| 收稿时间： | 2020/1/11 0:00:00 |
Research progress in biologic markers for prostate cancer |
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| ZHOU Pu-Fan,SHEN Rui-Lin,XIONG Lie,SHENG Tao,SONG Bao-Lin,WANG Xing-Bai,LU Hai-Juan,HUANG Tao,SHI Han-Qiang,SHAO Huan,HE Yan-Mei,WANG Xiao-Ting,JIANG Da-Wei and SHI Yan-Bo.Research progress in biologic markers for prostate cancer[J].Chinrse journal of Multiple Organ Diseases in the Elderly,2021,20(1):72-76. |
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| Authors: | ZHOU Pu-Fan SHEN Rui-Lin XIONG Lie SHENG Tao SONG Bao-Lin WANG Xing-Bai LU Hai-Juan HUANG Tao SHI Han-Qiang SHAO Huan HE Yan-Mei WANG Xiao-Ting JIANG Da-Wei and SHI Yan-Bo |
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| Institution: | (Central Laboratory of Molecular Medicine Research Center,Jiaxing Second Hospital,Jiaxing 314001,Zhejiang Province,China;Department of Urology Surgery,Jiaxing Second Hospital,Jiaxing 314001,Zhejiang Province,China;Department of Urology Surgery,Jiaxing Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medicial University,Jiaxing 314001,Zhejiang Province,China;Department of Radiology,Jiaxing Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medicial University,Jiaxing 314001,Zhejiang Province,China;Department of Ultrasound,Jiaxing Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medicial University,Jiaxing 314001,Zhejiang Province,China;Jiaxing Key Laboratory of Diabetic Angiopathy,Jiaxing 314001,Zhejiang Province,China) |
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| Abstract: | As one of the most common cancers in men,prostate cancer seriously threatens their health and safety.There are many challenges of prostate cancer in prediction,diagnosis and prognosis.Although biomarkers for the prostate cancer have shown certain clinic significance,they still have limitations when used alone.Accurate diagnosis,prevention of excessive biopsies,and construction of a diagnostic system of combined biomarkers are still trending research topics in the detection of prostate cancer.Here we analyze the cha-llenges in the detection of prostate cancer and review the research progress in biomarkers and related detection systems of prostate cancer. |
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| Keywords: | prostate cancer biomarker diagnosis |
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