| 弓形虫病核酸疫苗研究进展 |
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| 引用本文： | 范久波,舒衡平.弓形虫病核酸疫苗研究进展[J].中国病原生物学杂志,2008,3(11). |
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| 作者姓名： | 范久波 舒衡平 |
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| 作者单位： | 1. 湖北省襄樊市中心医院,湖北,襄樊,441021
2. 中南大学湘雅医学院寄生虫学教研室,湖南,长沙,410078 |
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| 摘 要： | 弓形虫病防制策略之一是研制安全有效的疫苗。弓形虫速殖子表面膜蛋白、棒状体蛋白、致密颗粒蛋白和微线体蛋白是重要的弓形虫抗原,这些抗原物质与弓形虫的侵袭性有关,且能诱导宿主的免疫反应。本文就近年来弓形虫病核酸疫苗研究现状作一综述。
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| 关 键 词： | 弓形虫病 DNA疫苗 质粒 综述 |
Research progress on nucleic acid vaccine of toxoplasmosis |
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| FAN Jiubo,SHU Heng-ping.Research progress on nucleic acid vaccine of toxoplasmosis[J].Journal of Pathogen Biology,2008,3(11). |
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| Authors: | FAN Jiubo SHU Heng-ping |
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| Abstract: | One of the most effective prevention and treatment strategies to toxoplasmosis is to develop safe and effective vaccines.Four main protein families of Toxoplasma gondii including surface membrane protein of tachyzoite,rhpotry protein,dense granule protein and microneme protein are important antigen,which are associated with invasion and could induce host immune response.This article reviewed the nucleic acid vaccine encoding above proteins of T.gondii studied in recent years. |
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| Keywords: | Toxoplasmosis DNA vaccine plasmid review |
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